Simon B R, Wu J S, Carlton M W, Kazarian L E, France E P, Evans J H, Zienkiewicz O C
Spine (Phila Pa 1976). 1985 Jul-Aug;10(6):494-507. doi: 10.1097/00007632-198507000-00003.
Finite element models (FEMs) and analytical and experimental models based on poroelastic constitutive laws were developed for rhesus spinal motion segments (SMSs). Long-time creep, transient creep, and impact were studied for SMSs with normal and simulated degenerated discs. The results suggested that long-time creep observed in excised SMSs may be reduced in the in vivo SMS. The fluid phase included in these FEMs was shown to play a significant role in the mechanical response of SMSs. Relative fluid motion fields predicted in the SMS could be related to nutritional paths to the avascular interior of the disc and were found to be very sensitive to changes in discal stiffness. Reduced disc height, increased discal bulge, altered fluid motion, and stresses were quantified and may be related to mechanical failure, disc degeneration, and low-back pain.
基于多孔弹性本构定律，为恒河猴脊柱运动节段（SMSs）建立了有限元模型（FEMs）以及分析和实验模型。对具有正常椎间盘和模拟退变椎间盘的SMSs进行了长期蠕变、瞬态蠕变和冲击研究。结果表明，在离体SMSs中观察到的长期蠕变在体内SMSs中可能会降低。这些有限元模型中包含的液相在SMSs的力学响应中起着重要作用。SMSs中预测的相对流体运动场可能与椎间盘无血管内部的营养路径有关，并且发现对椎间盘刚度的变化非常敏感。椎间盘高度降低、椎间盘膨出增加、流体运动改变和应力均被量化，并且可能与机械故障、椎间盘退变和腰痛有关。
