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孕期脉冲磁场暴露及其对核磁共振胎儿成像的影响:一项小鼠研究

Pulsed magnetic field exposure during pregnancy and implications for NMR foetal imaging: a study with mice.

作者信息

McRobbie D, Foster M A

出版信息

Magn Reson Imaging. 1985;3(3):231-4. doi: 10.1016/0730-725x(85)90351-0.

Abstract

Following the recent progress in NMR imaging of the foetus in utero an investigation has been made of the effect of exposure to strong pulsed magnetic fields on the pregnancy of mice and the post natal development of their litters. 23 pregnant mice received exposures ranging from 3.5-12kT/s with pulse periods in the range 0.33-0.56ms at various times during gestation. A similar number of pregnant mice served as controls. No adverse effect was observed on the pregnancy. There was no significant difference between the litter numbers and growth rates of the exposed litters compared with controls. The implications of these results are discussed with regard to the safety of NMR imaging during pregnancy.

摘要

随着近期子宫内胎儿核磁共振成像技术的进展,人们对暴露于强脉冲磁场对小鼠妊娠及其仔鼠出生后发育的影响进行了研究。23只怀孕小鼠在妊娠期的不同时间接受了强度范围为3.5 - 12kT/s、脉冲周期在0.33 - 0.56ms之间的照射。相同数量的怀孕小鼠作为对照。未观察到对妊娠有不良影响。与对照组相比,受照射仔鼠的窝仔数和生长速率没有显著差异。针对孕期核磁共振成像的安全性,对这些结果的意义进行了讨论。

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