Jacobson S, Trojanowski J Q
Brain Res. 1977 Aug 26;132(2):235-46. doi: 10.1016/0006-8993(77)90418-8.
In 6 adolescent rhesus monkeys, horseradish peroxidase (HRP) was injected into 6 regions of the dorsalateral convexity of the prefrontal granular cortex. The commissural connections originated in both homotopical and heterotopical zones of the hemisphere contralateral to the injection site. The areas affected by the injections, i.e. areas 46,45, 10, 9, 12 and 8a, received extensive homotopical interhemispheric input. HRP-labeled neurons were less extensive in heterotopical as opposed to homotopical cortex but they were seen in all 6 cases and were most common in prefrontal areas and less common in cingulate areas, areas 21 and 22 in the superior temporal sulcus and in insular cortex. The cells, whether of heterotopical or homotopical origin, were located primarily in layer III. The most common distribution pattern was a horizontal band of HRP-labeled neurons which waxed and waned in cell density especially in homotopical cortex or patches and clusters of labeled cells especially in heterotopical cotex. This waxing and waning and grouping of neurons in pathces and clusters may well represent a vertical type of organization to the neurons which give rise to the interhemispheric cortical afferents to prefrontal granular cortex in the monkey.
在6只青春期恒河猴中，将辣根过氧化物酶（HRP）注入前额叶颗粒皮质背外侧凸面的6个区域。连合连接起源于注射部位对侧半球的同位区和异位区。注射所影响的区域，即46、45、10、9、12和8a区，接受了广泛的同位性半球间输入。与同位皮质相比，HRP标记的神经元在异位皮质中的分布范围较小，但在所有6只猴子中均可见到，且在前额叶区域最为常见，在扣带区域、颞上沟的21和22区以及岛叶皮质中较少见。这些细胞，无论起源于异位还是同位，主要位于第III层。最常见的分布模式是一条HRP标记神经元的水平带，其细胞密度有增减变化，尤其是在同位皮质中，或者是标记细胞的斑块和簇，尤其是在异位皮质中。神经元在斑块和簇中的这种增减变化和聚集很可能代表了猴子前额叶颗粒皮质半球间皮质传入神经元的一种垂直组织类型。
