Du Jiahao, Yuan Tingting, Zhang Xiaotong, Tang Xuehui, Chen Wang, Zhu Fuyin, Xiao Changlin, Yuan Libo
Opt Express. 2025 Mar 10;33(5):11489-11499. doi: 10.1364/OE.554337.
Based on the annular-core capillary fiber, we propose and demonstrate an optical machine gun that uses photodynamic to achieve directional continuous emission of particles. By grinding the oblique cone at one end of the fiber and soldering it with the single-mode fiber, the liquid containing particles is injected into the air hole while the ring core is illuminated. A 12° cone structure is processed at the other end of the annular-core capillary fiber. The light is reflected by the cone structure to form a cone-shell light field, which realizes the guidance of the particle. The effects of different fluid injection pressures on particle velocity and the relationship between particle velocity and optical power were studied. The experimental results show that under the condition of a certain injection pressure, the greater the output power of the fiber end, the greater the particle velocity; when the output power is constant, the change of liquid injection pressure has little effect on the particle velocity. Finally, when the liquid injection pressure is 40 mbar, the path changes before and after the annular core is illuminated are compared. When the output power of the fiber end is 0 mW, the particle path is divergent. When the output power of the fiber end is 150 mW, the particle path is in linear motion. Due to the unique fiber structure, the proposed fiber device achieves continuous directional continuous emission of particles. It has important value and application prospects in cell manipulation and analysis in microfluidic chip systems and directional drug particle delivery of cells.
基于环形芯毛细管光纤，我们提出并演示了一种利用光动力学实现粒子定向连续发射的光学机枪。通过研磨光纤一端的斜锥并将其与单模光纤焊接，在环形芯被照亮的同时将含有粒子的液体注入气孔。在环形芯毛细管光纤的另一端加工一个12°的锥结构。光被锥结构反射形成锥壳光场，实现了对粒子的引导。研究了不同流体注入压力对粒子速度的影响以及粒子速度与光功率之间的关系。实验结果表明，在一定注入压力条件下，光纤末端的输出功率越大，粒子速度越大；当输出功率恒定时，液体注入压力的变化对粒子速度影响不大。最后，当液体注入压力为40毫巴时，比较了环形芯被照亮前后的路径变化。当光纤末端的输出功率为0毫瓦时，粒子路径发散。当光纤末端的输出功率为150毫瓦时，粒子路径呈直线运动。由于独特的光纤结构，所提出的光纤装置实现了粒子的连续定向发射。它在微流控芯片系统中的细胞操纵与分析以及细胞的定向药物粒子递送方面具有重要价值和应用前景。
