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止血带松开时机对全膝关节置换术中失血、手术时间及伤口情况的影响:一项前瞻性对照研究

Effect of Tourniquet Release Timing on Blood Loss, Surgical Time, and Wound Outcomes in Total Knee Arthroplasty: A Prospective Comparative Study.

作者信息

Hamad Ali M, Hammad Yazan S, Maswadeh Ahmad B, Sweidat Ali, Alisi Mohammed S, Ajlouni Jihad

机构信息

Trauma and Orthopaedics, Basildon University Hospital, Basildon, GBR.

Sarcoma and Complex Arthroplasty, Royal National Orthopaedic Hospital, London, GBR.

出版信息

Cureus. 2025 Aug 12;17(8):e89922. doi: 10.7759/cureus.89922. eCollection 2025 Aug.

DOI:10.7759/cureus.89922
PMID:40799665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12342694/
Abstract

Background The timing of tourniquet release in total knee arthroplasty (TKA) remains a topic of debate, with studies suggesting varying impacts on blood loss, operative time, and wound healing. Despite widespread global research, data from our region are limited, and objective assessment tools remain underutilised. Methods We conducted a prospective comparative study involving 113 patients undergoing primary TKA. Patients were assigned to one of two groups: Group A (tourniquet released before wound closure) and Group B (released after closure). All surgeries were standardised in terms of technique, prosthesis, and personnel. Outcomes included post-operative haemoglobin drop, intra-articular haematoma volume (measured via ultrasound), operative time, and wound healing at one-week follow-up. Results There was no significant difference between the two groups in haemoglobin drop (p = 0.877), intra-articular haematoma volume (p = 0.794), or operative time (p = 0.051). No wound complications were observed in either group. Conclusion The timing of tourniquet release, before or after wound closure, did not significantly affect post-operative blood loss, haematoma formation, operative time, or short-term wound healing. Surgeons may safely individualise release timing based on preference and intraoperative factors, provided tourniquet pressure and duration remain within safe thresholds.

摘要

背景

全膝关节置换术(TKA)中止血带松开的时机仍是一个有争议的话题,研究表明其对失血、手术时间和伤口愈合有不同影响。尽管全球范围内有广泛研究,但我们地区的数据有限,客观评估工具仍未得到充分利用。方法:我们进行了一项前瞻性比较研究,纳入113例行初次TKA的患者。患者被分为两组:A组(伤口闭合前松开止血带)和B组(伤口闭合后松开)。所有手术在技术、假体和人员方面均标准化。观察指标包括术后血红蛋白下降、关节内血肿体积(通过超声测量)、手术时间以及术后一周的伤口愈合情况。结果:两组在血红蛋白下降(p = 0.877)、关节内血肿体积(p = 0.794)或手术时间(p = 0.051)方面无显著差异。两组均未观察到伤口并发症。结论:伤口闭合前或后松开止血带的时机对术后失血、血肿形成、手术时间或短期伤口愈合无显著影响。只要止血带压力和持续时间保持在安全阈值内,外科医生可根据个人偏好和术中因素安全地个体化决定松开时机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fd7/12342694/61a96dfc1c46/cureus-0017-00000089922-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fd7/12342694/61a96dfc1c46/cureus-0017-00000089922-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fd7/12342694/61a96dfc1c46/cureus-0017-00000089922-i01.jpg

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本文引用的文献

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Role of tourniquet release timing on blood loss and functional outcomes in total knee arthroplasty: Insights from a low- and middle-income country.止血带松开时机对全膝关节置换术中失血及功能结局的影响:来自低收入和中等收入国家的见解
J Exp Orthop. 2024 Jul 24;11(3):e12075. doi: 10.1002/jeo2.12075. eCollection 2024 Jul.
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The Impact of Tourniquet Usage on TKA Outcome: A Single-Center Prospective Trial.
止血带使用对全膝关节置换术结果的影响:一项单中心前瞻性试验。
Medicina (Kaunas). 2023 Apr 30;59(5):870. doi: 10.3390/medicina59050870.
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