Mashhadi Faezeh, Sedghi Zahra, Hemmat Ava, Rivaz Raha, Roudi Fatemeh
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Nurs Res Pract. 2025 Aug 5;2025:2137328. doi: 10.1155/nrp/2137328. eCollection 2025.
Infertility significantly impacts individuals and society, necessitating effective strategies for its management. Among the various factors influencing female fertility, micronutrients play a crucial role in reproductive health by supporting oocyte quality, hormonal balance, and implantation processes. This narrative review examines the importance of optimal preconception micronutrient intake in enhancing female fertility. By analyzing research from various scientific databases, including PubMed, Google Scholar, and ScienceDirect, spanning from 2000 to April 2024, we highlight the impact of key micronutrients such as folate, vitamin D, iron, selenium, and antioxidants on fertility outcomes. Deficiencies in these nutrients have been associated with impaired ovarian function, disrupted menstrual cycles, and increased risk of pregnancy complications. Given the prevalence of micronutrient inadequacies among women of reproductive age, this review underscores the need for evidence-based nutritional interventions and standardized supplementation guidelines. The findings aim to bridge the gap between research and clinical practice, providing healthcare professionals with insights to optimize fertility care through targeted nutritional strategies.
不孕症对个人和社会都有重大影响，因此需要有效的管理策略。在影响女性生育能力的各种因素中，微量营养素通过支持卵母细胞质量、激素平衡和着床过程，在生殖健康中起着至关重要的作用。本叙述性综述探讨了孕前最佳微量营养素摄入对提高女性生育能力的重要性。通过分析2000年至2024年4月期间来自各种科学数据库（包括PubMed、谷歌学术和科学Direct）的研究，我们强调了叶酸、维生素D、铁、硒和抗氧化剂等关键微量营养素对生育结果的影响。这些营养素的缺乏与卵巢功能受损、月经周期紊乱以及妊娠并发症风险增加有关。鉴于育龄妇女中微量营养素不足的普遍情况，本综述强调了基于证据的营养干预措施和标准化补充指南的必要性。研究结果旨在弥合研究与临床实践之间的差距，为医疗保健专业人员提供见解，以便通过有针对性的营养策略优化生育护理。
