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[一例婴儿早期巨大颅内畸胎瘤。术后13年随访研究]

[A case of giant intracranial teratoma in early infancy. A 13 years' follow-up study after operation].

作者信息

Shirane R, Kayama T, Yoshimoto T, Suzuki J, Takaku A

出版信息

No Shinkei Geka. 1985 Oct;13(10):1103-7.

PMID:4080082
Abstract

A long-term result after total removal of a giant intracranial teratoma in early infancy is reported. The patient was a 5-month-old boy with vomiting, convulsion and right hemiparesis occurring acutely and shortly before admission. Plain skull films, In-113m brain scintiscanning and carotid angiography revealed a giant tumor located widely over both frontal lobes. At operation, the tumor, originated from the base of the anterior half of the cranial cavity. A mature teratoma weighing 320 grams was totally removed without sacrificing the adjacent brain and vessels. Both cerebral hemispheres were found severely compressed by the tumor. Postoperative respiratory and convulsive disorders were well controlled. The boy was discharged in the third month after operation. At present, 13 years after operation, he is developing normally for his age. In the junior high school, he studies and plays sports with no handicap. Computed tomography reveals no recurrence of the tumor. EEG shows reactive pattern of activity and small, but rare spikes in the frontal area. And his pituitary function is revealed to be normal.

摘要

报告了1例婴儿早期完全切除巨大颅内畸胎瘤后的长期结果。该患者为5个月大男孩,入院前不久急性出现呕吐、惊厥和右侧偏瘫。头颅平片、铟-113m脑闪烁扫描和颈动脉造影显示一个巨大肿瘤广泛位于双侧额叶。手术中,肿瘤起源于颅腔前半部分底部。一个重320克的成熟畸胎瘤被完全切除,未损伤相邻脑和血管。发现双侧大脑半球均被肿瘤严重压迫。术后呼吸和惊厥障碍得到良好控制。男孩术后第三个月出院。目前,术后13年,他发育正常,与同龄人无异。在初中,他学习和进行体育活动均无障碍。计算机断层扫描显示肿瘤无复发。脑电图显示活动反应模式,额叶有小的但罕见的尖波。并且他的垂体功能正常。

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