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持续心脏康复对心力衰竭患者心理和生理预后的影响——一项回顾性研究

The Impact of Continuous Cardiac Rehabilitation on the Psychological and Physiological Prognosis of Patients with Heart Failure-A Retrospective Study.

作者信息

Yan Li-Hua, Ge Yun, Wang Fei, Zhu Yu-Ling, Lu Li

机构信息

Department of Cardiovascular Internal Medicine, Nantong First Peoples' Hospital, Nantong University Second Affiliated Hospital, Nantong, Jiangsu, 226014, People's Republic of China.

Department of cardiovascular Surgery, Nantong First Peoples' Hospital, Nantong University Second Affiliated Hospital, Nantong, Jiangsu, 226014, People's Republic of China.

出版信息

Ther Clin Risk Manag. 2025 Aug 8;21:1227-1236. doi: 10.2147/TCRM.S529282. eCollection 2025.

Abstract

OBJECTIVE

This study aimed to assess the impact of continued cardiac rehabilitation on cardiac function, psychological well-being, and prognostic outcomes in patients diagnosed with heart failure and improved ejection fraction (HFimpEF).

METHODS

This study adopted a retrospective design, and a total of 150 patients with HFimpEF who experienced reduced ejection fraction after the first acute myocardial infarction were included. All patients underwent emergency percutaneous coronary intervention (PCI). Participants were categorized into a control group (n = 70) or an observation group (n = 80) based on their participation in ongoing cardiac rehabilitation. The follow-up period extended for one year. Comparative analyses were conducted to assess differences between the two groups in baseline characteristics, cardiac function, anxiety and depression scores, and the incidence of cardiovascular events.

RESULTS

No statistically significant differences were observed between the groups in terms of sex, age, past medical history, blood lipid levels, blood glucose levels, or renal function. Similarly, pre-treatment assessments of cardiac function, six-minute walk test results, Self-Rating Anxiety Scale (SAS) scores, Self-Rating Depression Scale (SDS) scores, or the incidence of cardiovascular events showed no significant differences. Compared to the control group, the observation group demonstrated significantly better cardiac function and six-minute walk test performance, along with significantly lower SAS and SDS scores. Furthermore, the incidence of heart failure and rehospitalization was significantly lower in the observation group than in the control group.

CONCLUSION

Sustained cardiac rehabilitation in patients with HFimpEF was associated with significant improvements in cardiac function, enhanced six-minute walk test performance, reduced anxiety and depression levels, and a lower incidence of heart failure and rehospitalization. These findings highlight the key role of sustained cardiac rehabilitation in improving clinical outcomes for patients with HFimpEF.

摘要

目的

本研究旨在评估持续心脏康复对诊断为射血分数改善的心力衰竭(HFimpEF)患者的心功能、心理健康和预后结果的影响。

方法

本研究采用回顾性设计,纳入了150例首次急性心肌梗死后射血分数降低的HFimpEF患者。所有患者均接受了急诊经皮冠状动脉介入治疗(PCI)。根据患者是否参与持续心脏康复,将参与者分为对照组(n = 70)或观察组(n = 80)。随访期为一年。进行比较分析以评估两组在基线特征、心功能、焦虑和抑郁评分以及心血管事件发生率方面的差异。

结果

两组在性别、年龄、既往病史、血脂水平、血糖水平或肾功能方面未观察到统计学上的显著差异。同样,心功能的治疗前评估、六分钟步行试验结果、自评焦虑量表(SAS)评分、自评抑郁量表(SDS)评分或心血管事件发生率也无显著差异。与对照组相比,观察组的心功能和六分钟步行试验表现明显更好,SAS和SDS评分显著更低。此外,观察组的心力衰竭和再住院发生率明显低于对照组。

结论

HFimpEF患者持续心脏康复与心功能显著改善、六分钟步行试验表现增强、焦虑和抑郁水平降低以及心力衰竭和再住院发生率降低相关。这些发现突出了持续心脏康复在改善HFimpEF患者临床结局中的关键作用。

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