Meena Varchasvi, Gill Nishant
Government Medical College Kota, Kota, Rajasthan, India.
Eur Arch Otorhinolaryngol. 2025 Aug 13. doi: 10.1007/s00405-025-09632-1.
Endotracheal intubation is a routine yet critical procedure during general anesthesia that can cause a spectrum of laryngeal injuries, potentially affecting vocal function and airway integrity. The route of intubation, oral versus nasal, may influence the incidence and severity of such injuries, but evidence is inconclusive.
This study aims to prospectively compare the incidence, severity, and clinical impact of laryngeal injuries following oral and nasal intubation in adult patients undergoing elective surgeries under general anesthesia.
A prospective observational study was conducted involving 67 patients scheduled for elective surgery with endotracheal intubation. Patients were allocated into oral (n = 35) and nasal (n = 32) intubation groups based on surgical requirements. Flexible fiberoptic laryngoscopy was performed within six hours of extubation to evaluate laryngeal injuries, graded using the Eckerbom classification. Hoarseness severity was assessed and recorded. Statistical analysis including chi-square tests and multivariate logistic regression identified predictors of injury and compared groups, with significance set at p < 0.05.
The incidence and severity of laryngeal injuries did not significantly differ between oral and nasal intubation groups (p = 0.67). Grade 0 injury (no visible abnormality) was predominant (oral 65.7%, nasal 71.9%). Hoarseness severity distribution was also comparable (p = 0.78). Multivariate analysis revealed no significant association between injury occurrence and variables including tube size, duration of intubation, or number of intubation attempts.
Oral and nasal routes of endotracheal intubation demonstrated comparable rates and severity of post-intubation laryngeal injuries in this cohort. Skilled intubation technique remains paramount to minimizing complications regardless of route.
气管插管是全身麻醉期间的一项常规但关键的操作,可导致一系列喉部损伤,可能影响发声功能和气道完整性。插管途径,经口与经鼻,可能会影响此类损伤的发生率和严重程度,但证据尚无定论。
本研究旨在前瞻性比较全身麻醉下接受择期手术的成年患者经口和经鼻插管后喉部损伤的发生率、严重程度及临床影响。
进行一项前瞻性观察性研究,纳入67例计划行气管插管择期手术的患者。根据手术需要将患者分为经口插管组(n = 35)和经鼻插管组(n = 32)。拔管后6小时内进行纤维喉镜检查以评估喉部损伤,采用埃克博姆分类法分级。评估并记录声音嘶哑的严重程度。包括卡方检验和多因素逻辑回归在内的统计分析确定损伤的预测因素并比较各组,显著性设定为p < 0.05。
经口和经鼻插管组喉部损伤的发生率和严重程度无显著差异(p = 0.67)。0级损伤(无可见异常)最为常见(经口65.7%,经鼻71.9%)。声音嘶哑严重程度分布也具有可比性(p = 0.78)。多因素分析显示损伤发生与包括导管尺寸、插管持续时间或插管尝试次数等变量之间无显著关联。
在该队列中,经口和经鼻气管插管途径显示出插管后喉部损伤的发生率和严重程度相当。无论插管途径如何,熟练的插管技术对于将并发症降至最低仍然至关重要。