Li Zhengtian, Ali Sikandar, Arain Muhammad Asif, Hassan Faiz-Ul, Nabi Fazul, Akhtar Muhammad Uzair, Yuan Hemei
College of Biological and Food Engineering, Qujing Normal University, Qujing, 655011, Yunnan, China.
Zhejiang Vegamax Biotechnology Co., Ltd, Huzhou, 313300, China.
Probiotics Antimicrob Proteins. 2025 Aug 13. doi: 10.1007/s12602-025-10708-x.
The poultry industry is under tremendous pressure to improve avian health and performance while reducing antibiotic dispensation due to concerns regarding antimicrobial resistance and food safety. In this scenario, postbiotics and parabiotics have emerged as viable alternatives to traditional feed additives. Postbiotics are bioactive substances generated subsequent to probiotic fermentation, encompassing microbial metabolites like short-chain fatty acids, peptides, and cell wall fragments, which provide various health advantages. Contrarily, parabiotics denote non-viable microbial cells or their constituents, which provide comparable immunomodulatory and gastrointestinal advantages without requiring live organisms. Both interventions play crucial roles in modulating gut microbiota, enhancing immune function, promoting nutrient absorption, and improving overall growth performance in poultry. The mechanisms through which these compounds exert their beneficial effects include modulation of gut microbiota, enhancement of immune response, and improvement of nutrient absorption. Recent studies demonstrated that postbiotics and parabiotics can curb down prevalence of gastrointestinal disorders and enhance feed conversion ratios (FCR) and overall performance in chicken. Through improving intestinal integrity and reducing harmful microbes, postbiotics improve nutrient absorption and growth rates, meanwhile alleviating the effects of strains like heat and health problems. Furthermore, the safety, stability, and ease of application of postbiotics and parabiotics in commercial feed formulations further assist and cultivate their extensive application. Current review emphasizes on the advantageous features and potential of postbiotics and parabiotics in mitigating prevalent poultry health and production-related constraints such as disease prevention, enhancement of FCR, weight gain, and egg production. This study examines prospective research avenues and potential obstacles in incorporating these biotic chemicals into conventional poultry management.
由于对抗菌素耐药性和食品安全的担忧,家禽业在改善禽类健康和生产性能的同时减少抗生素使用方面面临巨大压力。在这种情况下,后生元和副生物已成为传统饲料添加剂的可行替代品。后生元是益生菌发酵后产生的生物活性物质,包括短链脂肪酸、肽和细胞壁碎片等微生物代谢产物,具有多种健康益处。相反,副生物是指无活性的微生物细胞或其成分,它们能提供类似的免疫调节和胃肠道益处,而无需活的生物体。这两种干预措施在调节家禽肠道微生物群、增强免疫功能、促进营养吸收和改善整体生长性能方面都发挥着关键作用。这些化合物发挥有益作用的机制包括调节肠道微生物群、增强免疫反应和改善营养吸收。最近的研究表明,后生元和副生物可以降低鸡胃肠道疾病的发生率,提高饲料转化率(FCR)和整体生产性能。后生元通过改善肠道完整性和减少有害微生物,提高营养吸收和生长速度,同时减轻热应激和健康问题等应激因素的影响。此外,后生元和副生物在商业饲料配方中的安全性、稳定性和易用性进一步促进并推动了它们的广泛应用。当前的综述强调了后生元和副生物在缓解家禽常见健康和生产相关限制(如疾病预防、提高FCR、体重增加和产蛋量)方面的优势和潜力。本研究探讨了将这些生物化学品纳入传统家禽管理的潜在研究途径和障碍。