• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

剖宫产瘢痕妊娠宫腔镜治疗的病因及疗效:一项临床研究

Etiology and efficacy of hysteroscopic management in cesarean scar pregnancy: a clinical study.

作者信息

Zeng Yuhua, Luo Qiao, Ran Wei, Liu Jiashu, Zhang Chengju, Yong Min

机构信息

The Affiliated Hospital of North Sichuan Medical College, Department of Gynecology - Nanchong, China.

The Affiliated Hospital of North Sichuan Medical College, Department of Reproductive Medicine - Nanchong, China.

出版信息

Rev Assoc Med Bras (1992). 2025 Aug 8;71(7):e20241912. doi: 10.1590/1806-9282.20241912. eCollection 2025.

DOI:10.1590/1806-9282.20241912
PMID:40802397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12341425/
Abstract

OBJECTIVE

Cesarean scar pregnancy poses significant risks, including uterine scar rupture and increased postpartum hemorrhage. Effective diagnosis and treatment are critical to improving clinical outcomes. This study aimed to analyze the risk factors for cesarean scar pregnancy and evaluate the efficacy and safety of hysteroscopic diagnosis and treatment, providing a theoretical basis for clinical management.

METHODS

A total of 122 patients with cesarean scar pregnancy, diagnosed via vaginal ultrasound, were included in the study group and treated with hysteroscopic surgery. A total of 90 pregnant women with prior cesarean sections and normal intrauterine pregnancies were selected as the control group.

RESULTS

Logistic regression identified significant cesarean scar pregnancy risk factors: the number of uterine operations, the number of cesarean sections, and a time interval of ≤5 years since the last cesarean (p<0.05). After hysteroscopic treatment, the mean operation time, intraoperative bleeding, and surgical failure rate were 22.31±6.26 min, 57.23±9.12 mL, and 8.03%, respectively. Surgical failure was associated with gestational age, gestational sac position, gestational sac size, diverticulum angle, and blood β-human chorionic gonadotropin levels (p<0.05). Hysteroscopy demonstrated superior diagnostic accuracy over ultrasound for type II and type III cesarean scar pregnancy cases (p<0.05).

CONCLUSION

Hysteroscopic surgery improves treatment outcomes in cesarean scar pregnancy patients. Key risk factors for surgical failure include gestational age, gestational sac position, gestational sac size, diverticulum angle, and blood β-human chorionic gonadotropin levels. Early identification and management of these factors can enhance clinical outcomes and reduce complications.

摘要

目的

剖宫产瘢痕妊娠存在重大风险,包括子宫瘢痕破裂和产后出血增加。有效的诊断和治疗对于改善临床结局至关重要。本研究旨在分析剖宫产瘢痕妊娠的危险因素,并评估宫腔镜诊断和治疗的有效性及安全性,为临床管理提供理论依据。

方法

经阴道超声诊断为剖宫产瘢痕妊娠的122例患者纳入研究组,接受宫腔镜手术治疗。选取90例有剖宫产史且宫内妊娠正常的孕妇作为对照组。

结果

Logistic回归分析确定了剖宫产瘢痕妊娠的显著危险因素:子宫手术次数、剖宫产次数以及末次剖宫产术后间隔时间≤5年(p<0.05)。宫腔镜治疗后,平均手术时间、术中出血量及手术失败率分别为22.31±6.26分钟、57.23±9.12毫升和8.03%。手术失败与孕周、孕囊位置、孕囊大小、憩室角度及血β-人绒毛膜促性腺激素水平有关(p<0.05)。对于Ⅱ型和Ⅲ型剖宫产瘢痕妊娠病例,宫腔镜检查的诊断准确性优于超声检查(p<0.05)。

结论

宫腔镜手术可改善剖宫产瘢痕妊娠患者的治疗效果。手术失败的关键危险因素包括孕周、孕囊位置、孕囊大小、憩室角度及血β-人绒毛膜促性腺激素水平。早期识别和处理这些因素可改善临床结局并减少并发症。

相似文献

1
Etiology and efficacy of hysteroscopic management in cesarean scar pregnancy: a clinical study.剖宫产瘢痕妊娠宫腔镜治疗的病因及疗效:一项临床研究
Rev Assoc Med Bras (1992). 2025 Aug 8;71(7):e20241912. doi: 10.1590/1806-9282.20241912. eCollection 2025.
2
Hysteroscopic treatment of Cesarean Scar Pregnancy: A systematic review.宫腔镜治疗剖宫产术后子宫瘢痕妊娠:系统评价。
Eur J Obstet Gynecol Reprod Biol. 2022 Mar;270:42-49. doi: 10.1016/j.ejogrb.2021.12.038. Epub 2022 Jan 5.
3
Comparative Analysis of the Efficacy of Four Different Surgical Modalities in the Treatment of Cesarean Scar Pregnancy: A Multicenter Retrospective Study.四种不同手术方式治疗剖宫产瘢痕妊娠的疗效比较分析:一项多中心回顾性研究
Adv Ther. 2025 Mar;42(3):1448-1461. doi: 10.1007/s12325-024-03097-0. Epub 2025 Jan 24.
4
Conservative treatment of cesarean scar pregnancy with the combination of methotrexate and mifepristone: A systematic review.甲氨蝶呤联合米非司酮保守治疗剖宫产瘢痕妊娠的系统评价。
Womens Health (Lond). 2024 Jan-Dec;20:17455057241290424. doi: 10.1177/17455057241290424.
5
Reducing intraoperative hemorrhage in type II caesarean scar pregnancy: a study protocol comparing high-intensity focused ultrasound (HIFU) pretreatment vs. hysteroscopy-guided suction curettage-an open-label, 1:1 parallel-group, superiority-design investigator-initiated trial (IIT).减少Ⅱ型剖宫产瘢痕妊娠术中出血:一项比较高强度聚焦超声(HIFU)预处理与宫腔镜引导下吸刮术的研究方案——一项开放标签、1:1平行组、优效性设计的研究者发起试验(IIT)。
Trials. 2025 Aug 6;26(1):275. doi: 10.1186/s13063-025-08967-8.
6
Efficacy and safety of treatment modalities for cesarean scar pregnancy: a systematic review and network meta-analysis.剖宫产瘢痕妊娠治疗方式的疗效和安全性:系统评价和网络荟萃分析。
Am J Obstet Gynecol MFM. 2024 Aug;6(8):101328. doi: 10.1016/j.ajogmf.2024.101328. Epub 2024 Mar 12.
7
Cesarean Scar Pregnancies: A Systematic Review of Treatment Options.剖宫产瘢痕妊娠:治疗选择的系统评价
J Minim Invasive Gynecol. 2017 Sep-Oct;24(6):915-925. doi: 10.1016/j.jmig.2017.05.019. Epub 2017 Jul 18.
8
Local and Systemic Methotrexate Administration Along With Hysteroscopic Treatment of Cesarean Scar Pregnancy.局部及全身应用甲氨蝶呤联合宫腔镜治疗剖宫产瘢痕妊娠
J Obstet Gynaecol Can. 2025 Jul;47(7):102925. doi: 10.1016/j.jogc.2025.102925. Epub 2025 Jun 3.
9
Treatments for cesarean scar pregnancy: a systematic review and meta-analysis.剖宫产瘢痕妊娠的治疗方法:系统评价和荟萃分析。
J Matern Fetal Neonatal Med. 2024 Dec;37(1):2327569. doi: 10.1080/14767058.2024.2327569. Epub 2024 Oct 9.
10
Outcome of Cesarean scar pregnancy managed expectantly: systematic review and meta-analysis.期待治疗剖宫产瘢痕妊娠的结局:系统评价和荟萃分析。
Ultrasound Obstet Gynecol. 2018 Feb;51(2):169-175. doi: 10.1002/uog.17568.

本文引用的文献

1
Cesarean scar ectopic partial molar pregnancy: A case report and a review of literature.剖宫产瘢痕部位部分性葡萄胎妊娠:1例病例报告及文献复习
Case Rep Womens Health. 2023 Oct 12;39:e00555. doi: 10.1016/j.crwh.2023.e00555. eCollection 2023 Sep.
2
Retracted: Clinical Curative Effects and Influencing Factors of Uterine Artery Chemoembolization Combined with Uterine Curettage Treating with Cesarean Scar Pregnancy Patients.撤回:子宫动脉化疗栓塞联合刮宫术治疗剖宫产瘢痕妊娠患者的临床疗效及影响因素
Evid Based Complement Alternat Med. 2023 Jul 19;2023:9756578. doi: 10.1155/2023/9756578. eCollection 2023.
3
Cesarean scar pregnancy: a practical overview and our series of combined double step procedure management.剖宫产瘢痕妊娠:实用概述及我们的联合双步骤处理系列。
Minerva Obstet Gynecol. 2024 Oct;76(5):416-422. doi: 10.23736/S2724-606X.23.05291-0. Epub 2023 Jun 16.
4
Cesarean Scar Ectopic Pregnancy Clinical Classification System With Recommended Surgical Strategy.剖宫产瘢痕部位妊娠的临床分类系统与推荐的手术策略。
Obstet Gynecol. 2023 May 1;141(5):927-936. doi: 10.1097/AOG.0000000000005113. Epub 2023 Apr 5.
5
Outcome of cesarean scar pregnancy according to gestational age at diagnosis: A systematic review and meta-analysis.剖宫产瘢痕妊娠根据诊断时孕周的结局:一项系统评价和荟萃分析。
Eur J Obstet Gynecol Reprod Biol. 2021 Mar;258:53-59. doi: 10.1016/j.ejogrb.2020.11.036. Epub 2020 Nov 12.
6
Cesarean scar pregnancy combined with arteriovenous malformation successfully treated with transvaginal fertility-sparing surgery: A case report and literature review.经阴道保留生育功能手术成功治疗剖宫产瘢痕妊娠合并动静脉畸形:病例报告及文献复习
Medicine (Baltimore). 2020 Jul 31;99(31):e21432. doi: 10.1097/MD.0000000000021432.
7
Scoring system for the prediction of the successful treatment modality in women with cesarean scar pregnancy.剖宫产瘢痕妊娠患者治疗方式成功预测的评分系统。
Int J Gynaecol Obstet. 2019 Sep;146(3):289-295. doi: 10.1002/ijgo.12881. Epub 2019 Jun 19.