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Compounded hormonal pellets: a critical review of current evidence and risks.

作者信息

Wender Maria Celeste Osório, Steiner Marcelo Luis, Fernandes César Eduardo, Damásio Lia Cruz Vaz da Costa, Soares Júnior José Maria, Paiva Lúcia Helena Simões da Costa, Monteiro Ilza Maria Urbano, Quintairos Ricardo de Almeida, Macedo Clayton Luiz Dornelles, Silva Filho Agnaldo Lopes da

机构信息

Universidade Federal do Rio Grande do Sul, Faculty of Medicine, Department of Gynecology and Obstetrics - Porto Alegre (RS), Brazil.

Faculdade de Medicina do ABC, Department of Gynecology - Santo André (SP), Brazil.

出版信息

Rev Assoc Med Bras (1992). 2025 Aug 8;71(7):e20250121. doi: 10.1590/1806-9282.20250121. eCollection 2025.

DOI:10.1590/1806-9282.20250121
PMID:40802414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12341420/
Abstract
摘要

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本文引用的文献

1
Concerns about safety and efficacy of compounded bioidentical hormone therapy.关于复方生物等效激素疗法安全性和有效性的担忧。
Menopause. 2021 Jun 14;28(8):847-849. doi: 10.1097/GME.0000000000001813.
2
Low complication rates of testosterone and estradiol implants for androgen and estrogen replacement therapy in over 1 million procedures.在超过100万例手术中，睾酮和雌二醇植入物用于雄激素和雌激素替代疗法的并发症发生率较低。
Ther Adv Endocrinol Metab. 2021 May 27;12:20420188211015238. doi: 10.1177/20420188211015238. eCollection 2021.
3
Evaluation of the Quality of Perinatal Trials: Making the GRADE.围产期试验质量评估：GRADE 评级法。
Neonatology. 2021;118(3):378-383. doi: 10.1159/000516239. Epub 2021 May 4.
4
Compounded bioidentical hormone therapy: new recommendations from the 2020 National Academies of Sciences, Engineering, and Medicine.复方生物等同激素治疗：2020 年美国国家科学院、工程院和医学研究所的新建议。
Menopause. 2021 Mar 11;28(5):576-578. doi: 10.1097/GME.0000000000001735.
5
Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study.接受睾丸素植入治疗的女性中浸润性乳腺癌的发病率：一项前瞻性 10 年队列研究。
BMC Cancer. 2019 Dec 30;19(1):1271. doi: 10.1186/s12885-019-6457-8.
6
Global Consensus Position Statement on the Use of Testosterone Therapy for Women.关于女性使用睾酮疗法的全球共识立场声明。
Climacteric. 2019 Oct;22(5):429-434. doi: 10.1080/13697137.2019.1637079. Epub 2019 Sep 2.
7
Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data.女性使用睾酮的安全性和有效性：随机对照试验数据的系统评价和荟萃分析。
Lancet Diabetes Endocrinol. 2019 Oct;7(10):754-766. doi: 10.1016/S2213-8587(19)30189-5. Epub 2019 Jul 25.
8
Use of the etonogestrel implant and levonorgestrel intrauterine device beyond the U.S. Food and Drug Administration-approved duration.使用超过美国食品药品监督管理局批准期限的依托孕烯植入剂和左炔诺孕酮宫内节育器。
Obstet Gynecol. 2015 Mar;125(3):599-604. doi: 10.1097/AOG.0000000000000690.
9
Reduced breast cancer incidence in women treated with subcutaneous testosterone, or testosterone with anastrozole: a prospective, observational study.接受皮下注射睾酮或睾酮联合阿那曲唑治疗的女性乳腺癌发病率降低：一项前瞻性观察性研究。
Maturitas. 2013 Dec;76(4):342-9. doi: 10.1016/j.maturitas.2013.08.002. Epub 2013 Sep 10.
10
Testosterone implants in women: pharmacological dosing for a physiologic effect.女性睾酮植入物：实现生理效应的药理学剂量。
Maturitas. 2013 Feb;74(2):179-84. doi: 10.1016/j.maturitas.2012.11.004. Epub 2012 Dec 21.