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光生物调节联合新型修复材料用于磨牙切牙矿化不全牙齿的超敏反应控制和修复体寿命评估：一项随机对照双盲临床试验方案

Assessment of photobiomodulation combined with new restorative material for teeth with molar incisor hypomineralization on control of hypersensitivity and longevity of restorations: Protocol for a randomized controlled blind clinical trial.

作者信息

Ribeiro Caroline Diniz Pagani Vieira, Mandetta Amanda Rafaelly Honório, Pernomiam Fabiana Car, Camargo Caroline Cristina Batista De, Romano Iara Maria Freitas, Sobral Ana Paula Taboada, Leal Marcela Letícia, Mesquita-Ferrari Raquel Agnelli, Fernandes Kristianne Porta Santos, Horliana Anna Carolina Ratto Tempestini, Motta Lara Jansiski, Duran Cinthya Cosme Gutierrez, Bussadori Sandra Kalil

机构信息

Biophotonics Medicine Postgraduate Program, Universidade Nove de Julho, São Paulo, Brazil.

Postgraduate Programme in Rehabilitation Sciences, Universidade Nove de Julho, São Paulo, Brazil.

出版信息

PLoS One. 2025 Aug 13;20(8):e0329641. doi: 10.1371/journal.pone.0329641. eCollection 2025.

DOI:10.1371/journal.pone.0329641
PMID:40802785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12349719/
Abstract

ClinicalTrials.gov NCT06538142.

摘要

临床试验.gov标识符：NCT06538142

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ab8/12349719/e1b9629143e6/pone.0329641.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ab8/12349719/e1b9629143e6/pone.0329641.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ab8/12349719/e1b9629143e6/pone.0329641.g001.jpg

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本文引用的文献

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Antimicrobial photodynamic therapy and deproteinization in teeth with molar incisor hypomineralization: a case series.磨牙切牙矿化不全牙齿的抗菌光动力疗法和脱蛋白作用：病例系列
Transl Pediatr. 2025 Feb 28;14(2):311-321. doi: 10.21037/tp-24-480. Epub 2025 Feb 25.
2
Molar Incisor Hypomineralization: Optimizing Treatment Protocols for Hypersensitivity: A Randomized Clinical Trial.磨牙切牙矿化不全：优化牙齿敏感的治疗方案：一项随机临床试验。
Dent J (Basel). 2024 Jun 19;12(6):186. doi: 10.3390/dj12060186.
3
Evaluation of antimicrobial photodynamic therapy and minimal intervention associated with deproteinisation in permanent teeth with molar incisor hypomineralisation: study protocol for a clinical, controlled, blinded trial.
评价抗菌光动力疗法和去蛋白化联合应用于磨牙-切牙牙釉质发育不全恒牙的最小侵入治疗：一项临床对照双盲试验的研究方案。
BMJ Open. 2023 Dec 14;13(12):e076226. doi: 10.1136/bmjopen-2023-076226.
4
Photobiomodulation and glass ionomer sealant as complementary treatment for hypersensitivity in molar incisor hypomineralisation in children: protocol for a blinded randomised clinical trial.光生物调节与玻璃离子水门汀联合治疗儿童磨牙釉质不全症牙本质过敏症的双盲随机临床试验方案
BMJ Open. 2023 Jun 14;13(6):e068102. doi: 10.1136/bmjopen-2022-068102.
5
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Int J Mol Sci. 2022 Sep 30;23(19):11594. doi: 10.3390/ijms231911594.
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Hypersensitivity in teeth affected by molar-incisor hypomineralization (MIH).磨牙-切牙釉质发育不全（MIH）影响牙齿的超敏反应。
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Molar-incisor hypomineralisation: an updated view for aetiology 20 years later.恒磨牙牙釉质发育不全：发病 20 年后的新观点。
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