Shumye Abebech Fikade, Bekele Matiyas Mamo
Department of Optometry, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia
Department of Optometry, College of Medicine and Health Sciences, Comprehensive Specialized Hospital, University of Gondar, Gondar, Ethiopia.
BMJ Open. 2025 Aug 12;15(8):e098561. doi: 10.1136/bmjopen-2024-098561.
This study aimed to assess the prevalence and associated factors of primary open-angle glaucoma (POAG) among adult diabetic patients in Northwest Ethiopia, 2023.
An institution-based cross-sectional study was conducted using a systematic random sampling method.
The study was conducted in the University of Gondar, Debre Tabor, Felege Hiwot, Tibebe Ghion and Debre Markos Comprehensive Specialized Hospitals in Northwest Ethiopia.
The study included 1174 adult diabetic patients aged 18 years or older who had resided in Northwest Ethiopia for more than 6 months.
The primary outcome was the prevalence of POAG among adult diabetic patients in Northwest Ethiopia, 2023. The second outcome was the associated factors of POAG among adult diabetic patients.
A total of 1134 study participants participated, with a response rate of 96.5%. The median age of the participants was 53 years, with an IQR of 37-62 years. The prevalence of POAG was 14.37% (95% CI 12.30 to 16.30). Older age (adjusted OR (AOR)=2.97, 95% CI 1.25 to 7.04), long duration of diabetic mellitus (AOR=3.54, 95% CI 2.27 to 5.51), poor blood glucose level (AOR=2.61, 95% CI 1.50 to 4.54), proliferative diabetic retinopathy (PDR) (AOR=4.91, 95% CI 2.10 to 11.46) and intraocular pressure (IOP) (AOR=9.15, 95% CI 6.01 to 13.93) were significantly associated factors with POAG.
This study revealed that the proportion of POAG among adult diabetic patients was high. Older age, long duration of diabetes mellitus, poor blood glucose level, PDR and IOP were positively associated with POAG.
本研究旨在评估2023年埃塞俄比亚西北部成年糖尿病患者中原发性开角型青光眼(POAG)的患病率及相关因素。
采用系统随机抽样方法进行基于机构的横断面研究。
研究在埃塞俄比亚西北部的贡德尔大学、德布雷塔博尔、费莱格希沃特、蒂贝贝吉翁和德布雷马尔科斯综合专科医院开展。
研究纳入了1174名年龄在18岁及以上、居住在埃塞俄比亚西北部超过6个月的成年糖尿病患者。
主要观察指标是2023年埃塞俄比亚西北部成年糖尿病患者中POAG的患病率。第二个观察指标是成年糖尿病患者中POAG的相关因素。
共有1134名研究参与者,应答率为96.5%。参与者的年龄中位数为53岁,四分位间距为37 - 62岁。POAG的患病率为14.37%(95%置信区间12.30至16.30)。年龄较大(调整后比值比(AOR)=2.97,95%置信区间1.25至7.04)、糖尿病病程较长(AOR=3.54,95%置信区间2.27至5.51)、血糖水平较差(AOR=2.61,95%置信区间1.50至4.54)、增殖性糖尿病视网膜病变(PDR)(AOR=4.91,95%置信区间2.10至11.46)和眼压(IOP)(AOR=9.15,95%置信区间6.01至13.93)是与POAG显著相关的因素。
本研究表明成年糖尿病患者中POAG的比例较高。年龄较大、糖尿病病程较长、血糖水平较差、PDR和IOP与POAG呈正相关。