Wenzel Caitlin J, Mochal-King Cathleen A, Eddy Alison L, Bowser Jacquelyn E, Wills Robert W, Jumper W Isaac, Claude Andrew, Swiderski Cyprianna E
Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Starkville, MS 39762, USA.
Department of Equine Studies, Johnson & Wales University, Providence, RI 02903, USA.
Animals (Basel). 2025 Aug 4;15(15):2276. doi: 10.3390/ani15152276.
The aim of this retrospective clinical study was to assess surgical duration and surgical and post-operative complications associated with Video-Assisted Thoracoscopic Surgery (VATS) and lung biopsy in horses with severe Equine Pasture Asthma (EPA) and paired control horses. Twelve horses (6 EPA-affected, 6 control) were sex, age and breed matched. Twenty-four thoracic surgeries were performed. Surgery of each matched pair (EPA-affected and healthy) was performed during asthma exacerbation (summer) and remission (winter). Surgical times were shorter with uncomplicated thoracoscopy (85 min) and significantly longer ( < 0.001) when intra-operative complications necessitated conversion to thoracotomy (156 min). The overall surgical time of EPA-affected horses during asthma exacerbation was significantly longer than control horses at any time point, predicted mean difference of 78 min ( < 0.05). When comparing EPA-affected horses to themselves during asthma exacerbation and remission, surgical times were significantly longer ( < 0.01) with a predicted mean difference of 98 min; this effect of seasonality did not occur amongst control horses. Intra-operative surgical complications (6/24) were evenly divided between EPA and control horses, however, only severe EPA horses in exacerbation were noted to have lung hyperinflation. Post-operative complications: fever, colic, hemothorax, pneumothorax, subcutaneous emphysema, surgical site infection, and/or laminitis occurred in 13/24 surgical procedures (54%). No fatalities resulted from these procedures.
这项回顾性临床研究的目的是评估与视频辅助胸腔镜手术（VATS）和肺活检相关的手术时长以及手术和术后并发症，研究对象为患有严重马牧场型哮喘（EPA）的马匹和配对的对照马匹。12匹马（6匹受EPA影响，6匹对照）在性别、年龄和品种上进行了匹配。共进行了24例胸外科手术。每对匹配的马匹（受EPA影响的和健康的）的手术在哮喘发作期（夏季）和缓解期（冬季）进行。单纯胸腔镜检查的手术时间较短（85分钟），而当术中出现并发症需要转为开胸手术时，手术时间显著延长（<0.001）（156分钟）。在任何时间点，受EPA影响的马匹在哮喘发作期的总体手术时间均显著长于对照马匹，预测平均差异为78分钟（<0.05）。将受EPA影响的马匹在哮喘发作期和缓解期进行自身比较时，手术时间显著延长（<0.01），预测平均差异为98分钟；对照马匹未出现这种季节性影响。术中手术并发症（6/24）在EPA组和对照组马匹中分布均匀，然而，仅在发作期的严重EPA马匹中发现有肺过度充气。术后并发症：发热、绞痛、血胸、气胸、皮下气肿、手术部位感染和/或蹄叶炎发生在13/24例手术中（54%）。这些手术未导致死亡。
