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弥漫性大B细胞淋巴瘤的靶向治疗和免疫治疗

Targeted Therapies and Immunotherapies for Diffuse Large B-Cell Lymphoma.

作者信息

Chaudhari Jahnavi, Shah Nikesh N

机构信息

Department of Internal Medicine, HCA Florida Oak Hill Hospital, Brooksville, FL 34613, USA.

USF Health Morsani College of Medicine, Tampa, FL 33602, USA.

出版信息

Cancers (Basel). 2025 Jul 30;17(15):2517. doi: 10.3390/cancers17152517.

DOI:10.3390/cancers17152517
PMID:40805213
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12345741/
Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive non-Hodgkin lymphoma (NHL) [...].

摘要

弥漫性大B细胞淋巴瘤(DLBCL)是最常见的侵袭性非霍奇金淋巴瘤(NHL)[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4999/12345741/30db1235fa23/cancers-17-02517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4999/12345741/30db1235fa23/cancers-17-02517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4999/12345741/30db1235fa23/cancers-17-02517-g001.jpg

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本文引用的文献

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Blood. 2025 Jul 15. doi: 10.1182/blood.2025029117.
2
Atezolizumab, obinutuzumab and venetoclax for the treatment of patients with relapsed/refractory B non-Hodgkin lymphoma: Final analysis of a phase II trial from the LYSA group.阿替利珠单抗、奥滨尤妥珠单抗和维奈克拉治疗复发/难治性B细胞非霍奇金淋巴瘤患者:来自LYSA组的一项II期试验的最终分析
Br J Haematol. 2025 Jul;207(1):110-122. doi: 10.1111/bjh.20109. Epub 2025 Apr 26.
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Effect of Intravenous Immunoglobulin (IVIG) Supplementation on infection-free survival in recipients of BCMA-directed bispecific antibody therapy for multiple myeloma.
静脉注射免疫球蛋白(IVIG)补充对接受靶向BCMA双特异性抗体治疗的多发性骨髓瘤患者无感染生存期的影响。
Blood Cancer J. 2025 Apr 23;15(1):74. doi: 10.1038/s41408-025-01282-0.
4
Atezolizumab consolidation in patients with high-risk diffuse large B-cell lymphoma in complete remission after R-CHOP.阿替利珠单抗用于经R-CHOP治疗后完全缓解的高危弥漫性大B细胞淋巴瘤患者的巩固治疗。
Blood Adv. 2025 Jul 22;9(14):3530-3539. doi: 10.1182/bloodadvances.2024015226.
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Glofitamab in refractory or relapsed diffuse large B cell lymphoma after failing CAR-T cell therapy: a phase 2 LYSA study.在CAR-T细胞治疗失败后,使用glofitamab治疗难治性或复发性弥漫性大B细胞淋巴瘤:一项2期LYSA研究。
Nat Cancer. 2025 Apr 3. doi: 10.1038/s43018-025-00941-2.
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