Pirri Carmelo, Manocchio Nicola, Sorbino Andrea, Pirri Nina, Foti Calogero
Department of Neurosciences, Institute of Human Anatomy, University of Padua, 35121 Padova, Italy.
Physical and Rehabilitation Medicine, Department of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Healthcare (Basel). 2025 Jul 23;13(15):1793. doi: 10.3390/healthcare13151793.
: Percutaneous electrolysis (PE) is a minimally invasive procedure that utilizes galvanic current delivered through a needle. PE is increasingly employed for musculoskeletal disorders, despite the scarcity of scientific evidence supporting its use. The aim of this systematic review is to synthesize the existing evidence and explore the applications of PE in rehabilitation. : In line with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic search was conducted across the PubMed, Web of Science, Scopus, and PEDro databases from inception to July 2025. The search strategy employed the term "Percutaneous Electrolysis" without applying additional filters or time restrictions, ensuring a comprehensive search. Cited references from screened articles were also evaluated for potential inclusion. Studies were included if they met the following criteria: peer-reviewed articles, intervention-based research, relevance to the topic, and publication in English. : Of the 181 papers retrieved, 143 were excluded for various reasons, leaving 38 studies. The evidence suggests that PE appears effective in reducing pain and improving function, particularly when combined with exercises such as eccentric training or stretching, though inconsistencies in protocols and patient characteristics, along with unclear mechanisms, show that it warrants further investigation. : In conclusion, while PE emerges as a promising therapeutic strategy for musculoskeletal disorders, its full integration into rehabilitation practice necessitates further rigorous research to standardize treatment protocols, elucidate the underlying mechanism, and validate its cost-effectiveness. These steps are essential to establish PE as a robust and evidence-based option within the field of rehabilitation.
经皮电解（PE）是一种微创手术，它利用通过针传递的直流电。尽管支持其使用的科学证据很少，但PE越来越多地用于肌肉骨骼疾病。本系统评价的目的是综合现有证据，并探索PE在康复中的应用。
根据系统评价和荟萃分析的首选报告项目指南，从数据库创建到2025年7月，在PubMed、科学网、Scopus和PEDro数据库中进行了系统检索。检索策略使用了“经皮电解”一词，未应用其他筛选条件或时间限制，以确保全面检索。还对筛选文章的参考文献进行了潜在纳入评估。如果研究符合以下标准，则纳入研究：同行评审文章、基于干预的研究、与主题相关以及以英文发表。
在检索到的181篇论文中，143篇因各种原因被排除，剩下38项研究。证据表明，PE似乎在减轻疼痛和改善功能方面有效，特别是与离心训练或拉伸等运动相结合时，尽管方案和患者特征存在不一致，且机制尚不清楚，这表明它值得进一步研究。
总之，虽然PE作为一种治疗肌肉骨骼疾病的有前景的治疗策略出现，但其完全融入康复实践需要进一步严格的研究，以规范治疗方案、阐明潜在机制并验证其成本效益。这些步骤对于将PE确立为康复领域中一种强大且基于证据的选择至关重要。
