利用和驾驭生成式人工智能减轻儿童神经发育障碍(NDDs)的负担。

Leveraging and Harnessing Generative Artificial Intelligence to Mitigate the Burden of Neurodevelopmental Disorders (NDDs) in Children.

作者信息

Oleribe Obinna Ositadimma

机构信息

Department of Health Sciences, School of Public Health and Health Sciences, California State University, Dominguez Hills, Carson, CA 90747, USA.

Center for Family Health Initiative (CFHI), Orange, CA 92865, USA.

出版信息

Healthcare (Basel). 2025 Aug 4;13(15):1898. doi: 10.3390/healthcare13151898.

Abstract

Neurodevelopmental disorders (NDDs) significantly impact children's health and development. They pose a substantial burden to families and the healthcare system. Challenges in early identification, accurate and timely diagnosis, and effective treatment persist due to overlapping symptoms, lack of appropriate diagnostic biomarkers, significant stigma and discrimination, and systemic barriers. Generative Artificial Intelligence (GenAI) offers promising solutions to these challenges by enhancing screening, diagnosis, personalized treatment, and research. Although GenAI is already in use in some aspects of NDD management, effective and strategic leveraging of evolving AI tools and resources will enhance early identification and screening, reduce diagnostic processing by up to 90%, and improve clinical decision support. Proper use of GenAI will ensure individualized therapy regimens with demonstrated 36% improvement in at least one objective attention measure compared to baseline and 81-84% accuracy relative to clinician-generated plans, customize learning materials, and deliver better treatment monitoring. GenAI will also accelerate NDD-specific research and innovation with significant time savings, as well as provide tailored family support systems. Finally, it will significantly reduce the mortality and morbidity associated with NDDs. This article explores the potential of GenAI in transforming NDD management and calls for policy initiatives to integrate GenAI into NDD management systems.

摘要

神经发育障碍(NDDs)对儿童的健康和发育有重大影响。它们给家庭和医疗系统带来了沉重负担。由于症状重叠、缺乏合适的诊断生物标志物、严重的耻辱感和歧视以及系统性障碍,早期识别、准确及时诊断和有效治疗方面仍存在挑战。生成式人工智能(GenAI)通过加强筛查、诊断、个性化治疗和研究,为这些挑战提供了有前景的解决方案。尽管GenAI已在NDD管理的某些方面得到应用,但有效且战略性地利用不断发展的人工智能工具和资源将加强早期识别和筛查,将诊断处理时间最多减少90%,并改善临床决策支持。正确使用GenAI将确保个性化治疗方案,与基线相比,至少一项客观注意力指标有36%的改善,相对于临床医生制定的方案,准确率达到81 - 84%,定制学习材料,并提供更好的治疗监测。GenAI还将加速NDD特定领域的研究和创新,大幅节省时间,并提供量身定制的家庭支持系统。最后,它将显著降低与NDDs相关的死亡率和发病率。本文探讨了GenAI在改变NDD管理方面的潜力,并呼吁采取政策举措将GenAI纳入NDD管理系统。

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