Bahadur A
Pol J Pharmacol Pharm. 1985 Jul-Aug;37(4):463-8.
Effect of cis-platin (cis-dichlorodiamine platinum II) on Dalton's lymphoma in syngeneic DBA and allogeneic Swiss white mice was studied. Normal healthy mice were immunized with cis-platin incubated cells and challenged to check the immunity developed. In vitro assay of cell mediated immunity was investigated by the capillary cell migration inhibition of reticuloendothelial cells from both DBA and Swiss white (treated as well as normal) mice against the specific tumor antigen. Cis-platin treatment results in specific enhancement of host cellular immune system.
研究了顺铂（顺二氯二氨铂II）对同基因DBA小鼠和异基因瑞士白化小鼠的道尔顿淋巴瘤的影响。用经顺铂孵育的细胞对正常健康小鼠进行免疫，并进行攻毒以检查所产生的免疫力。通过检测DBA小鼠和瑞士白化小鼠（处理组和正常组）的网状内皮细胞针对特异性肿瘤抗原的毛细管细胞迁移抑制情况，对细胞介导免疫进行体外测定。顺铂治疗可导致宿主细胞免疫系统的特异性增强。
