Mauriello Leopoldo, Cuozzo Alessandro, Pezzella Vitolante, Iorio-Siciliano Vincenzo, Isola Gaetano, Spagnuolo Gianrico, Ramaglia Luca, Blasi Andrea
School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Unit of Periodontology, Department of General Surgery and Medical-Surgical Specialties, University of Catania, 95124 Catania, Italy.
J Clin Med. 2025 Jul 23;14(15):5210. doi: 10.3390/jcm14155210.
Third lower molar (TLM) extraction is one of the most common oral surgical procedures, often accompanied by postoperative pain and inflammation. In order to treat postoperative pain, different methods are used, mainly based on painkillers. PBMT may represent an adjunct to pain management. This narrative review aims to evaluate the efficacy of PBMT in reducing postoperative pain following TLM extraction. A comprehensive search was conducted to identify studies examining the use of PBMT for postoperative pain relief after TLM extraction. Four randomized controlled trials (RCTs) met the inclusion criteria and were analyzed qualitatively. Two studies showed statistically significant reductions in pain with PBMT. Kahraman et al. reported lower pain scores in the intraoral PBMT ( = 0.001), with up to a 3.2-point reduction on the Visual Analog Scale (VAS). De Paula et al. found improved pain control using a dual-wavelength (808 + 660 nm) versus a single wavelength protocol ( = 0.031). The remaining studies showed non-significant results toward pain reduction. PBMT shows encouraging results in managing postoperative pain after TLM extraction, specifically with intraoral and multi-wavelength protocols. However, further studies are necessary to confirm its clinical utility.
拔除下颌第三磨牙（TLM）是最常见的口腔外科手术之一，术后常伴有疼痛和炎症。为了治疗术后疼痛，人们采用了不同的方法，主要基于止痛药。低强度激光疗法（PBMT）可能是疼痛管理的一种辅助手段。本叙述性综述旨在评估PBMT在减轻TLM拔除术后疼痛方面的疗效。进行了全面检索，以确定研究PBMT用于TLM拔除术后疼痛缓解的研究。四项随机对照试验（RCT）符合纳入标准，并进行了定性分析。两项研究显示PBMT在疼痛减轻方面有统计学意义。卡拉曼等人报告说，口腔内PBMT的疼痛评分较低（P = 0.001），视觉模拟量表（VAS）上的疼痛评分最多降低3.2分。德保拉等人发现，与单波长方案相比，双波长（808 + 660 nm）方案在疼痛控制方面有所改善（P = 0.031）。其余研究显示在减轻疼痛方面无显著结果。PBMT在管理TLM拔除术后疼痛方面显示出令人鼓舞的结果，特别是采用口腔内和多波长方案时。然而，需要进一步研究以证实其临床效用。
