Gadamer Anna Maria, Miklaszewski Piotr, Janiszewska-Bil Dominika, Lyssek-Boroń Anita, Dobrowolski Dariusz, Wylęgała Edward, Grabarek Beniamin Oskar, Krysik Katarzyna
Department of Ophthalmology, Trauma Centre, St. Barbara Hospital, 41-200 Sosnowiec, Poland.
Department of Ophthalmology, Faculty of Medicine, Academy of Silesia, 40-555 Katowice, Poland.
J Clin Med. 2025 Jul 28;14(15):5325. doi: 10.3390/jcm14155325.
: Keratoconus (KC) is a bilateral asymmetric corneal ectasia characterized by progressive corneal thinning, irregular astigmatism, and impaired visual acuity. The National Eye Institute (NEI) developed the Visual Function Questionnaire (VFQ-25) to assess the impact of visual impairment on quality of life. This study aimed to evaluate the effect of penetrating keratoplasty (PKP) on quality of life and visual acuity in KC patients one year postoperatively. : A retrospective study was conducted between January 2018 and December 2022 at the Ophthalmology Department of Saint Barbara Hospital, Trauma Center, Sosnowiec, Poland. A total of 71 patients (86 eyes) diagnosed with KC underwent PKP. The VFQ-25 questionnaire and visual acuity measurements were assessed preoperatively and one year postoperatively. : The study cohort included 71 patients (20 females, 28.17%; 51 males, 71.83%). Preoperative visual acuity ranged from less than 0.05 on the Snellen chart to 0.5. Postoperatively, visual acuity improved to a range of 0.1-1.0. A visual acuity of 1.0 was achieved in 21 eyes (24.42%; 5 females, 24%; 16 males, 76%), with a statistically significant improvement ( < 0.01). The mean VFQ-25 composite score increased from 57.96 (±17.58) preoperatively to 81.42 (±14.66) postoperatively ( < 0.001). Domains with the lowest preoperative scores were "role difficulties," "general vision," and "mental health," while "color vision" scored highest. : PKP significantly enhances both objective visual acuity and subjective quality of life in KC patients, as reflected in VFQ-25 questionnaire outcomes.
圆锥角膜（KC）是一种双侧不对称的角膜扩张性疾病，其特征为角膜进行性变薄、不规则散光和视力受损。美国国立眼科研究所（NEI）开发了视觉功能问卷（VFQ - 25）来评估视力损害对生活质量的影响。本研究旨在评估穿透性角膜移植术（PKP）对KC患者术后一年生活质量和视力的影响。：2018年1月至2022年12月在波兰索斯诺维茨创伤中心圣巴巴拉医院眼科进行了一项回顾性研究。共有71例被诊断为KC的患者（86只眼）接受了PKP。术前和术后一年评估VFQ - 25问卷和视力测量结果。：研究队列包括71例患者（20例女性，占28.17%；51例男性，占71.83%）。术前视力在斯内伦视力表上范围为低于0.05至0.5。术后，视力提高到0.1 - 1.0范围。21只眼（占24.42%；5例女性，占24%；16例男性，占76%）达到了1.0的视力，有统计学显著改善（<0.01）。VFQ - 25综合平均得分从术前的57.96（±17.58）提高到术后的81.42（±14.66）（<0.001）。术前得分最低的领域是“角色困难”、“总体视力”和“心理健康”，而“色觉”得分最高。：PKP显著提高了KC患者的客观视力和主观生活质量，这在VFQ - 25问卷结果中得到体现。
