Czechowska Beata, Chrzczanowicz Jacek, Gawor Rafał, Zarzycka Aleksandra, Kostka Tomasz, Kostka Joanna
Department of Methodology of Teaching Movement, Medical University of Lodz, Pl. Hallera 1, 90-647 Lodz, Poland.
Cardiac Rehabilitation Centre, Copernicus Memorial Hospital, Popioly 40, 93-438 Lodz, Poland.
J Clin Med. 2025 Aug 7;14(15):5561. doi: 10.3390/jcm14155561.
: Diabetes mellitus (DM) is a significant factor affecting prognosis and functional capacity in patients after cardiovascular events. This study aimed to assess the impact of coexisting diabetes on exercise tolerance and hemodynamic parameters in patients qualified for cardiac rehabilitation. : A total of 452 patients (86 women, 366 men; mean age 63.21 ± 7.16 years) who had experienced cardiovascular incidents, including 226 individuals with coexisting DM (DM group) and 226 age- (±1 year) and sex-matched individuals without DM (non-DM group), were included in the analysis. All participants underwent an exercise test using a bicycle ergometer. Clinical data, comorbidities, medication use, left ventricular ejection fraction, and exercise test parameters were evaluated. : Patients with DM displayed a higher number of comorbidities (4.29 ± 1.26 vs. 3.19 ± 1.30; < 0.001), greater medication use (8.71 ± 2.16 vs. 7.83 ± 2.05; < 0.001), higher body mass (86.93 ± 13.35 kg vs. 80.92 ± 15.25 kg; < 0.001), and a lower left ventricular ejection fraction (48.78 ± 8.99% vs. 50.01 ± 8.40%; = 0.002) compared to those in the non-DM group. Diabetic patients also exhibited lower exercise capacity, expressed as peak power per kilogram of body mass (1.05 ± 0.27 W/kg vs. 1.16 ± 0.31 W/kg; < 0.001). No significant differences were observed regarding absolute peak power or maximum heart rate. : In patients after cardiovascular incidents, the presence of diabetes is associated with reduced relative exercise capacity and lower ejection fraction.
糖尿病（DM）是影响心血管事件后患者预后和功能能力的重要因素。本研究旨在评估并存糖尿病对符合心脏康复条件患者运动耐量和血流动力学参数的影响。
共有452例经历过心血管事件的患者（86例女性，366例男性；平均年龄63.21±7.16岁）纳入分析，其中包括226例并存糖尿病患者（糖尿病组）和226例年龄（±1岁）和性别匹配的非糖尿病患者（非糖尿病组）。所有参与者均使用自行车测力计进行运动测试。评估临床数据、合并症、药物使用情况、左心室射血分数和运动测试参数。
与非糖尿病组相比，糖尿病患者的合并症数量更多（4.29±1.26对3.19±1.30；P<0.001），药物使用量更大（8.71±2.16对7.83±2.05；P<0.001），体重更高（86.93±13.35 kg对80.92±15.25 kg；P<0.001），左心室射血分数更低（48.78±8.99%对50.01±8.40%；P = 0.002）。糖尿病患者的运动能力也较低，以每千克体重的峰值功率表示（1.05±0.27 W/kg对1.16±0.31 W/kg；P<0.001）。在绝对峰值功率或最大心率方面未观察到显著差异。
在心血管事件后的患者中，糖尿病的存在与相对运动能力降低和射血分数降低有关。
