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一种评估药物对鱼类[具体阶段未给出]阶段疗效的新方法。

A novel method for evaluating the efficacy of pharmaceuticals against the stage of in fish.

作者信息

Hu Guang-Ran, Zeng Qing-Wen, Huang Ke, Zou Hong, Li Wen-Xiang, Wu Shan-Gong, Wang Gui-Tang, Li Ming

机构信息

State Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology (CAS), and Key Laboratory of Aquaculture Disease Control, Ministry of Agriculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China.

Guangzhou Customs District Technology Center, Guangzhou, 510623, China.

出版信息

MethodsX. 2025 Jul 2;15:103480. doi: 10.1016/j.mex.2025.103480. eCollection 2025 Dec.

Abstract

This study presents a description of a novel apparatus for evaluating the efficacy of pharmaceuticals against the stage of the fish parasite . The apparatus comprises a transparent acrylic rectangular cuboid, a metal wire mesh, and a gridded black acrylic bottom plate. Fallen trophonts are caught on the bottom plate and are separated from the fish by the mesh. The efficacy of a pharmaceutical can be assessed by adding it to the aquarium and subsequently counting the number of live tomonts and differntiating rate on the bottom plate. This device facilitates observation and enhances the precision and accuracy of pharmaceutical evaluation experiments.

摘要

本研究介绍了一种用于评估药物对鱼类寄生虫阶段疗效的新型装置。该装置包括一个透明的丙烯酸矩形长方体、一个金属丝网和一个带网格的黑色丙烯酸底板。脱落的滋养体被捕集在底板上,并通过网与鱼分离。通过将药物添加到水族箱中,随后计算底板上活包囊体的数量和分化率,可以评估药物的疗效。该装置便于观察,并提高了药物评估实验的精度和准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54e8/12343348/5c77ca3a9ade/ga1.jpg

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