Modderkolk Linda, Göttgens Irene, van den Hurk Lori, Oertelt-Prigione Sabine
Gender Unit, Department of Primary and Community Care, Radboud University Medical Centre, Nijmegen, Netherlands.
AG 10 Sex- and Gender-sensitive Medicine, Medical Faculty OWL, University of Bielefeld, Bielefeld, Germany.
Int J Cardiol Cardiovasc Risk Prev. 2025 Jul 29;27:200480. doi: 10.1016/j.ijcrp.2025.200480. eCollection 2025 Dec.
Ischemia with No Obstructive Arteries (INOCA) is a condition characterized by an elusive diagnosis and a significant impact on patients' quality of life. Recent evidence challenges previous assumptions about INOCA's benign prognosis, emphasizing the increased downstream risks associated with condition. A 2020 Dutch Society for Cardiology (NVVC) recommendation aims to guide cardiologists in the management of INOCA, but its adoption in practice varies. This study explores the interconnecting factors influencing the uptake of the INOCA recommendation.
A qualitative interview study was performed to investigate cardiologists' adoption of the 2020 NVVC INOCA recommendation in the Netherlands, utilizing the Theoretical Domains Framework and COM-B model. A diverse sample of Dutch cardiologists was recruited and digital semi-structured interviews were conducted and analyzed using directed content analysis.
A total of 14 Dutch cardiologists (6 women, 8 men) was interviewed to explore factors influencing their uptake of the 2020 NVVC INOCA recommendation. The immediate influences on uptake were grouped into three domains: capabilities, opportunities, and motivation according to the COM-B model. Most importantly, underlying assumptions about the evidence base, diagnostic accuracy, and gendered stereotypes significantly influenced recommendation uptake.
Underlying assumptions about the disease entity and the affected patient, which are seldom investigated in implementation research, significantly affect the overall uptake of the INOCA guideline. Careful investigation of these assumptions is necessary to challenge them and foster an environment conducive to the uptake of structural implementation measures.
无阻塞性动脉缺血(INOCA)是一种诊断困难且对患者生活质量有重大影响的疾病。近期证据对先前关于INOCA预后良好的假设提出了挑战,强调了该疾病相关的下游风险增加。2020年荷兰心脏病学会(NVVC)的一项建议旨在指导心脏病专家对INOCA的管理,但在实际应用中存在差异。本研究探讨了影响INOCA建议采纳的相互关联因素。
采用定性访谈研究,利用理论领域框架和COM-B模型,调查荷兰心脏病专家对2020年NVVC的INOCA建议的采纳情况。招募了不同的荷兰心脏病专家样本,进行了数字半结构化访谈,并使用定向内容分析法进行分析。
共访谈了14名荷兰心脏病专家(6名女性,8名男性),以探讨影响他们采纳2020年NVVC的INOCA建议的因素。根据COM-B模型,对采纳的直接影响分为三个领域:能力、机会和动机。最重要的是,关于证据基础、诊断准确性和性别刻板印象的潜在假设显著影响了建议的采纳。
关于疾病实体和受影响患者的潜在假设在实施研究中很少被调查,但会显著影响INOCA指南的总体采纳。仔细研究这些假设对于挑战它们并营造有利于采纳结构性实施措施的环境是必要的。