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小儿睾丸微结石症的临床与影像学诊断:医生的两难困境

Clinical and imaging diagnosis of pediatric testicular microlithiasis: a physician's dilemma.

作者信息

Habachi Ghada, Kerkeni Yosra, Riadh Jouini

机构信息

Faculty of Medicine, Tunis El Manar University, Tunis, Tunisia.

Department of Pediatric Surgery "A", "Bechir Hamza" Children's Hospital of Tunis, Tunis El Manar University, Tunis, Tunisia.

出版信息

Front Pediatr. 2025 Jul 30;13:1554081. doi: 10.3389/fped.2025.1554081. eCollection 2025.

DOI:10.3389/fped.2025.1554081
PMID:40809380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12343687/
Abstract

Testicular microlithiasis (TM) is a relatively rare and incompletely understood condition, particularly in the pediatric population. Its clinical significance and optimal diagnostic and therapeutic management remain subjects of ongoing debate. In order to clarify current practices and guide clinical decision-making, we conducted a literature review of recent studies published using the search terms , , , and . The primary objective of this review was to propose a standardized diagnostic management algorithm based on the available evidence. The nature of testicular microlithiasis remains a subject of ongoing debate. In the absence of definitive evidence, continued follow-up appears to be the safest approach to minimize the risk of delayed diagnosis in the event of malignant transformation or tumor development. Routine scrotal examination should be encouraged and properly taught, particularly to adolescents and their caregivers. Ultrasonographic (US) surveillance, while not mandatory, should be considered when accessible, especially in individuals with additional risk factors.

摘要

睾丸微石症(TM)是一种相对罕见且尚未完全了解的病症,在儿科人群中尤为如此。其临床意义以及最佳诊断和治疗管理仍是持续争论的话题。为了阐明当前的做法并指导临床决策,我们对使用搜索词 、 、 和 发表的近期研究进行了文献综述。本综述的主要目的是根据现有证据提出一种标准化的诊断管理算法。睾丸微石症的性质仍是一个持续争论的话题。在缺乏确凿证据的情况下,持续随访似乎是将恶性转化或肿瘤发生时延迟诊断风险降至最低的最安全方法。应鼓励并正确教授常规阴囊检查,尤其是对青少年及其护理人员。超声(US)监测虽非强制性,但在可行时应予以考虑,特别是对于有其他风险因素的个体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3754/12343687/2e9a231c9914/fped-13-1554081-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3754/12343687/7f6607d0a1e9/fped-13-1554081-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3754/12343687/2e9a231c9914/fped-13-1554081-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3754/12343687/7f6607d0a1e9/fped-13-1554081-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3754/12343687/2e9a231c9914/fped-13-1554081-g002.jpg

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本文引用的文献

1
Is testicular microlithiasis associated with decreased semen parameters? a systematic review.睾丸微石症与精液参数降低有关吗?一项系统评价。
Basic Clin Androl. 2024 Dec 5;34(1):23. doi: 10.1186/s12610-024-00238-x.
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Testicular biopsies in men with testicular microlithiasis and additional risk factors for cancer: A case series.睾丸微石症合并其他癌症危险因素男性的睾丸活检:病例系列研究。
Andrology. 2024 Nov;12(8):1764-1770. doi: 10.1111/andr.13610. Epub 2024 Feb 20.
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Association Between Testicular Microlithiasis and Histological Subtype in Testicular Cancer.
睾丸微结石症与睾丸癌组织学亚型之间的关联
Cureus. 2022 Oct 5;14(10):e29946. doi: 10.7759/cureus.29946. eCollection 2022 Oct.
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Testicular microlithiasis in paediatric patients with Klinefelter syndrome from infancy till adolescence: early start of degenerative process in the testes-preliminary results.婴儿期至青春期克氏综合征患儿的睾丸微石症:睾丸退行性变过程的早期开始——初步结果。
Eur J Pediatr. 2023 Jan;182(1):225-235. doi: 10.1007/s00431-022-04663-w. Epub 2022 Oct 25.
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Is testicular microlithiasis associated with testicular pathologies in children?睾丸微石症是否与儿童睾丸病变有关?
Pediatr Surg Int. 2022 Sep;38(9):1317-1319. doi: 10.1007/s00383-022-05177-0. Epub 2022 Jul 12.
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Incidence of testicular microlithiasis after orchidopexy for cryptorchidism and its risk factors: A retrospective cohort study.隐睾症行睾丸固定术后微石症的发生率及其危险因素:一项回顾性队列研究。
J Pediatr Urol. 2022 Jun;18(3):377.e1-377.e5. doi: 10.1016/j.jpurol.2022.03.030. Epub 2022 Apr 13.
7
Management of Testicular Microlithiasis.睾丸微石症的处理。
Eur Urol Focus. 2021 Sep;7(5):940-942. doi: 10.1016/j.euf.2021.09.020. Epub 2021 Sep 29.
8
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J Pediatr Urol. 2021 Dec;17(6):815-831. doi: 10.1016/j.jpurol.2021.06.013. Epub 2021 Jun 13.
9
The role of scrotal ultrasonography from infancy to puberty.阴囊超声检查在婴儿期至青春期的作用。
Andrology. 2021 Sep;9(5):1306-1321. doi: 10.1111/andr.13056. Epub 2021 Jun 11.
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