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新型冠状病毒肺炎(COVID-19)引发的封锁措施对津巴布韦布拉瓦约市接受抗逆转录病毒治疗(ART)的艾滋病毒/艾滋病患者坚持ART治疗的影响。

The impact of COVID-19-induced lockdowns on Antiretroviral-Therapy (ART) adherence by HIV/AIDs patients on ART in the city of Bulawayo in Zimbabwe.

作者信息

Jamela Mjabuli, Özdal Macide Artac

机构信息

European University of Lefke, Lefke, Northern Cyprus TR-10 Mersin, Turkey, 99010.

出版信息

Afr Health Sci. 2024 Jun;24(2):19-31. doi: 10.4314/ahs.v24i2.4.

DOI:10.4314/ahs.v24i2.4
PMID:40809568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12341185/
Abstract

BACKGROUND

Zimbabwe has one of the highest HIV prevalence rates in the world. HIV treatment was initiated in 2004 and expanded to 94% coverage rate by the 2020.

OBJECTIVES

i) to determine the level of treatment adherence during COVID-19-induced lockdowns and ii) to investigate the key determinants of adherence to ART during COVID-19-induced lockdowns.

METHODS

The cross sectional study involved 392 people living with HIV (PLHIV) and was conducted at nine health facilities in Bulawayo City. Data was analysed using the Shapiro-wilk test for normality, Chi-squared test, Kaiser-Meyer-Olkin (KMO), Bartlett's test, exploratory factor analysis, reliability analysis, scree plot, correlation analysis and multiple linear regression analysis.

RESULTS

94.6% of the respondents took their ARTs on time, and 90.6% did not miss any treatment review. The factors influencing treatment adherence were health systems (beta value 0.334), Family support (beta value 0.138) and knowledge/understanding of treatment (beta value 0.109). Health outcome concerns (beta value -0.194) and food security and livelihoods (beta value 0.191).

CONCLUSION

Three factors had a positive impact on treatment adherence namely, functional health systems, family support, and knowledge or understanding of health treatment, while two factors namely health outcome concerns and food security and livelihoods negatively impacted treatment adherence.

摘要

背景

津巴布韦是世界上艾滋病毒感染率最高的国家之一。2004年开始实施艾滋病毒治疗,到2020年覆盖率扩大到94%。

目的

i)确定在新冠疫情引发的封锁期间的治疗依从性水平;ii)调查在新冠疫情引发的封锁期间抗逆转录病毒治疗依从性的关键决定因素。

方法

这项横断面研究涉及392名艾滋病毒感染者,在布拉瓦约市的9个卫生设施进行。使用夏皮罗-威尔克正态性检验、卡方检验、凯泽-迈耶-奥尔金(KMO)检验、巴特利特检验、探索性因子分析、可靠性分析、碎石图、相关性分析和多元线性回归分析对数据进行分析。

结果

94.6%的受访者按时服用抗逆转录病毒药物,90.6%的人没有错过任何治疗复查。影响治疗依从性的因素有卫生系统(β值0.334)、家庭支持(β值0.138)和对治疗的知识/理解(β值0.109)。对健康结果的担忧(β值-0.194)以及粮食安全和生计(β值0.191)。

结论

三个因素对治疗依从性有积极影响,即功能健全的卫生系统、家庭支持以及对健康治疗的知识或理解,而两个因素,即对健康结果的担忧以及粮食安全和生计对治疗依从性有负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3479/12341185/410ab49a02a5/AFHS2402-0019Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3479/12341185/410ab49a02a5/AFHS2402-0019Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3479/12341185/410ab49a02a5/AFHS2402-0019Fig1.jpg

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