Bamidele Janet, Abiodun Olumide, Sodeinde Kolawole, Bitto Terkaa, Alabi Adekunle, Akinleye Callistus, Adejumo Olusola, Daniel Olusoji
Olabisi Onabanjo University Teaching Hospital, Department of community medicine and Primary care.
Babcock University, Community Medicine.
Afr Health Sci. 2024 Jun;24(2):71-80. doi: 10.4314/ahs.v24i2.9.
Drug-resistant tuberculosis (DR-TB) continues to be a public health concern. Several factors, including the disease itself, affect the quality of life of DR-TB patients. This study aimed to assess the quality of life (QOL) and associated factors of drug-resistant tuberculosis patients in Nigeria.
A cross-sectional study of 165 participants using an interviewer-administered 26-item World Health Organization Quality of life Brief version (WHOQOL-BREF) tool. Two questions assessed overall quality of life and general health while twenty-four questions assessed the physical, social, psychological and environmental domains of QOL. Continuous variables were summarized using means, standard deviations while association between categorical variables were analyzed using Chisquare test. Binary logistic regression model assessed the predictors of QOL with statistical significance at p<0.05.
Mean age was 35.63 ± 11.36. The overall quality of life was 3.96±0.82. The environmental domain had the highest mean quality of life (64.9±14.6), while the physical domain had the lowest (59.2±11.2). Marital status, family size, and support from the TB programme were associated with a good QOL.
Overall quality of life was good. Continued financial and social support for drug-resistant tuberculosis patients on treatment by the national tuberculosis control programme is recommended.
耐多药结核病(DR-TB)仍然是一个公共卫生问题。包括疾病本身在内的几个因素会影响耐多药结核病患者的生活质量。本研究旨在评估尼日利亚耐多药结核病患者的生活质量(QOL)及其相关因素。
采用访谈式26项世界卫生组织生活质量简表(WHOQOL-BREF)工具,对165名参与者进行横断面研究。两个问题评估总体生活质量和一般健康状况,而另外24个问题评估生活质量的身体、社会、心理和环境领域。连续变量用均值和标准差进行汇总,分类变量之间的关联采用卡方检验进行分析。二元逻辑回归模型评估生活质量的预测因素,p<0.05具有统计学意义。
平均年龄为35.63±11.36。总体生活质量为3.96±0.82。环境领域的平均生活质量最高(64.9±14.6),而身体领域最低(59.2±11.2)。婚姻状况、家庭规模和结核病项目的支持与良好的生活质量相关。
总体生活质量良好。建议国家结核病控制项目继续为接受治疗的耐多药结核病患者提供经济和社会支持。