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受裂变中子和γ射线照射的小鼠的寿命缩短。V. 单次低剂量的进一步研究。

Life shortening in mice exposed to fission neutrons and gamma rays. V. Further studies with single low doses.

作者信息

Thomson J F, Williamson F S, Grahn D

出版信息

Radiat Res. 1985 Dec;104(3):420-8.

PMID:4080984
Abstract

Data are presented on the mean after survival of female B6CF1 mice exposed to single doses of neutrons (1 to 40 rad) or gamma rays (22.5, 45, and 90 rad). For gamma-ray exposures and for neutron exposures up to 10 rad, the dose-response curves are indistinguishable from linear; higher neutron doses produce significant departures and linearity. Consequently, in these data, an upper limit of the relative biological effectiveness (RBE) exists for life shortening from all causes of death after single neutron exposures; this value is 15.0 +/- 5.1. The RBE depends on the cause of death, ranging from 2 to 5 for lymphoreticular tumors to 23-24 for lung tumors.

摘要

本文呈现了雌性B6CF1小鼠单次暴露于中子(1至40拉德)或γ射线(22.5、45和90拉德)后的平均存活时间数据。对于γ射线照射以及10拉德以下的中子照射,剂量反应曲线与线性曲线无法区分;更高的中子剂量会产生显著偏差且偏离线性。因此,在这些数据中,单次中子照射后因各种死因导致寿命缩短的相对生物效应(RBE)存在上限;该值为15.0±5.1。RBE取决于死因,从淋巴网状肿瘤的2至5到肺部肿瘤的23 - 24不等。

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Radiat Res. 1985 Dec;104(3):420-8.
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