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[辐照去交感神经大鼠的脑酶活性]

[Brain enzyme activity in irradiated sympathectomized rats].

作者信息

Pikulev A T, Kukulianskaia M F, Khripchenko I P, Gavriliuk L P, Pevzner I A

出版信息

Radiobiologiia. 1985 Nov-Dec;25(6):804-5.

PMID:4080998
Abstract

The results are reviewed from studies of activity of hexokinase (2.7.1.1.EC), dehydrogenase glucose-6-phosphate (1.1.1.49 EC), and cholinesterase (3.1.1.7 EC) in subcellular fractions of rat brain at the background of chemical sympathectomy induced by long-term administration of guanethidine and subsequent irradiation with a dose of 7 Gy. In conditions of sympathectomy, the enzyme activity is inhibited; in irradiated sympathectomized rats, activity of hexokinase and cholinesterase increases to reach the level of that of intact animals while dehydrogenase remains inhibited.

摘要

对长期给予胍乙啶诱导化学性交感神经切除并随后接受7戈瑞剂量照射的大鼠脑亚细胞组分中己糖激酶(EC 2.7.1.1)、6-磷酸葡萄糖脱氢酶(EC 1.1.1.49)和胆碱酯酶(EC 3.1.1.7)活性的研究结果进行了综述。在交感神经切除的情况下,酶活性受到抑制;在接受照射的交感神经切除大鼠中,己糖激酶和胆碱酯酶的活性增加,达到完整动物的水平,而脱氢酶仍受到抑制。

相似文献

1
[Brain enzyme activity in irradiated sympathectomized rats].[辐照去交感神经大鼠的脑酶活性]
Radiobiologiia. 1985 Nov-Dec;25(6):804-5.
2
[Activity of hexokinase, glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in intact and sympathectomized rat testes exposed to hormones].[暴露于激素下的完整及交感神经切除大鼠睾丸中己糖激酶、葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶的活性]
Vopr Med Khim. 1973;19(6):582-6.
3
[Activity of hexokinase and dehydrogenases of the pentose phosphate pathway in sympathectomized rat testes].[去交感神经大鼠睾丸中己糖激酶和磷酸戊糖途径脱氢酶的活性]
Zh Evol Biokhim Fiziol. 1973 Jan-Feb;9(1):51-5.
4
[Blood pressure lability in the sympathectomized rat].
C R Acad Sci III. 1989;308(8):219-22.
5
[Changes in fructosediphosphate aldolase and glucose-6-phosphate dehydrogenase activity after irradiation of animals with an absolute lethal dose of gamma rays].[动物接受绝对致死剂量γ射线照射后果糖二磷酸醛缩酶和葡萄糖-6-磷酸脱氢酶活性的变化]
Radiobiologiia. 1985 Mar-Apr;25(2):245-9.
6
[Nature of changes in the activity of certain enzymes of energy metabolism in the liver after partial sympathectomy].[部分交感神经切除术后肝脏能量代谢某些酶活性变化的性质]
Vopr Med Khim. 1976 Nov-Dec;22(6):808-12.
7
[Effect of cAMP on hexokinase and glucose-6-phosphate dehydrogenase isoenzymes in different white rat tissues].[环磷酸腺苷对不同大鼠组织中己糖激酶和葡萄糖-6-磷酸脱氢酶同工酶的影响]
Biull Eksp Biol Med. 1981 Jul;92(7):52-4.
8
[Age changes in rat vasomotor reflexes and sympathetic neuron ultrastructure following chemical sympathectomy].
Biull Eksp Biol Med. 1975 Jun;79(6):21-4.
9
[Morphofunctional characteristics of the myocardium in chronically sympathectomized rats].
Biull Eksp Biol Med. 1982 May;93(5):34-7.
10
Arterial pressure control in the sympathectomized rat.交感神经切除大鼠的动脉血压控制
Kidney Int Suppl. 1992 Jun;37:S19-23.