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Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series.

作者信息

Ogbutor Chino, Chen Li-Chi, Kalil Luiza L, Kelley Kristen J, Craiglow Brittany G, King Brett, Senna Maryanne Makredes

机构信息

Department of Dermatology, Lahey Hospital & Medical Center, Burlington, Massachusetts.

Department of Dermatology, Yale School of Medicine, New Haven, Connecticut.

出版信息

Int J Womens Dermatol. 2025 Aug 13;11(3):e218. doi: 10.1097/JW9.0000000000000218. eCollection 2025 Oct.

DOI:10.1097/JW9.0000000000000218
PMID:40810112
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12348381/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8485/12348381/86709e235c87/jw9-11-e218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8485/12348381/86709e235c87/jw9-11-e218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8485/12348381/86709e235c87/jw9-11-e218-g001.jpg

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1
Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series.斑秃患者因妊娠停用及重新启用 Janus 激酶抑制剂:病例系列报道
Int J Womens Dermatol. 2025 Aug 13;11(3):e218. doi: 10.1097/JW9.0000000000000218. eCollection 2025 Oct.
2
Evaluating Current and Emergent JAK Inhibitors for Alopecia Areata: A Narrative Review.评估斑秃的现有和新型JAK抑制剂:一项叙述性综述
Dermatol Ther (Heidelb). 2025 Aug 12. doi: 10.1007/s13555-025-01517-9.
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Efficacy and safety of the oral Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor ritlecitinib over 24 months: integrated analysis of the ALLEGRO phase IIb/III and long-term phase III clinical studies in alopecia areata.口服酪氨酸激酶3/肝细胞癌中表达的酪氨酸激酶家族激酶抑制剂芦可替尼24个月的疗效和安全性:斑秃的ALLEGRO IIb/III期和长期III期临床研究的综合分析
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本文引用的文献

1
Current evidence on safety of Janus kinase inhibitors in pregnancy and lactation.
J Am Acad Dermatol. 2025 May;92(5):1082-1084. doi: 10.1016/j.jaad.2024.10.108. Epub 2024 Dec 3.
2
The burden of alopecia areata: A scoping review focusing on quality of life, mental health and work productivity.斑秃的负担:一项聚焦于生活质量、心理健康和工作效率的范围综述。
J Eur Acad Dermatol Venereol. 2023 Jan 27. doi: 10.1111/jdv.18926.
3
Maintenance, withdrawal, and re-treatment with ritlecitinib and brepocitinib in patients with alopecia areata in a single-blind extension of a phase 2a randomized clinical trial.在一项2a期随机临床试验的单盲扩展试验中,对斑秃患者使用利特昔替尼和布雷西替尼进行维持、撤药及再治疗。
J Am Acad Dermatol. 2022 Aug;87(2):390-393. doi: 10.1016/j.jaad.2021.12.008. Epub 2021 Dec 13.
4
Alopecia areata: a review of disease pathogenesis.斑秃:疾病发病机制的综述。
Br J Dermatol. 2018 Nov;179(5):1033-1048. doi: 10.1111/bjd.16808. Epub 2018 Sep 9.
5
Assessing quality of life in Alopecia areata patients in China.评估中国斑秃患者的生活质量。
Psychol Health Med. 2015;20(1):97-102. doi: 10.1080/13548506.2014.894641. Epub 2014 Mar 17.