Hoban Connor W, Zhang Chao, Jin Yuxuan, Saluan Paul M, Farrow Lutul D, Rosneck James T, Jones Morgan H, Miniaci Anthony, Leo Brian M, Parker Richard D, Kattan Michael W, Spindler Kurt P
Department of Orthopaedics, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Orthop J Sports Med. 2025 Aug 12;13(8):23259671251321831. doi: 10.1177/23259671251321831. eCollection 2025 Aug.
A decreased hamstring tendon (HT) autograft diameter has been associated with higher rates of failure in primary anterior cruciate ligament reconstruction (ACLR).
To determine whether an HT autograft diameter ≥8 mm has an effect on the risk of graft failure and subsequent knee surgery after ACLR in a prospective cohort.
Cohort study; Level of evidence, 2.
Patients undergoing primary ACLR with an HT autograft were included and followed prospectively for 2 years to capture subsequent surgery events performed in either knee. The effect of HT autograft diameter on the risk of subsequent surgery was analyzed using multivariable regression modeling that adjusted for patient age, sex, body mass index, and Marx activity score.
Of 421 eligible patients, 381 (90.5%) had a minimum 2-year follow-up and were included in analysis. The median autograft diameter was 8.5 mm (interquartile range, 8.0-9.0 mm); 90.8% of patients received an autograft with a diameter ≥8 mm. There were 59 patients (15.5%) who underwent subsequent ipsilateral knee surgery, including 27 patients (7.1%) who had graft failure and underwent revision ACLR within 2 years. HT autograft diameter was not associated with the risk of all subsequent ipsilateral knee surgery (odds ratio [OR], 0.87 [95% CI, 0.56-1.36]; = .536) or revision ACLR (OR, 0.71 [95% CI, 0.38-1.33]; = .286). A Marx activity score ≥12 was associated with an increased risk of all subsequent ipsilateral knee surgery (OR, 2.55 [95% CI, 1.41-4.59]; = .002). Younger age was associated with an increased risk of revision ACLR (OR, 0.16 [95% CI, 0.05-0.51]; = .002).
A minimum HT autograft diameter of 8 mm was not associated with the risk of revision ACLR or other subsequent surgery in the ipsilateral or contralateral knee. This study may guide intraoperative decision making regarding HT autograft implementation in ACLR.
在初次前交叉韧带重建术(ACLR)中,绳肌腱(HT)自体移植物直径减小与更高的失败率相关。
确定HT自体移植物直径≥8mm对前瞻性队列中ACLR后移植物失败风险及后续膝关节手术的影响。
队列研究;证据等级,2级。
纳入接受HT自体移植物初次ACLR的患者,并进行前瞻性随访2年,以记录双侧膝关节随后进行的手术事件。使用多变量回归模型分析HT自体移植物直径对后续手术风险的影响,该模型对患者年龄、性别、体重指数和马克思活动评分进行了调整。
421例符合条件的患者中,381例(90.5%)进行了至少2年的随访并纳入分析。自体移植物直径中位数为8.5mm(四分位间距,8.0 - 9.0mm);90.8%的患者接受了直径≥8mm的自体移植物。有59例患者(15.5%)随后接受了同侧膝关节手术,其中27例患者(7.1%)移植物失败并在2年内接受了ACLR翻修术。HT自体移植物直径与所有后续同侧膝关节手术风险(比值比[OR],0.87[95%可信区间,0.56 - 1.36];P = 0.536)或ACLR翻修术风险(OR,0.71[95%可信区间,0.38 - 1.33];P = 0.286)均无关。马克思活动评分≥12与所有后续同侧膝关节手术风险增加相关(OR,2.55[95%可信区间,1.41 - 4.59];P = 0.002)。年龄较小与ACLR翻修术风险增加相关(OR,0.16[95%可信区间,0.05 - 0.51];P = 0.002)。
HT自体移植物最小直径8mm与ACLR翻修术风险或同侧或对侧膝关节其他后续手术风险无关。本研究可为ACLR中HT自体移植物应用的术中决策提供指导。