Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy; Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy; Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Arthroscopy. 2024 Jul;40(7):2121-2131.e1. doi: 10.1016/j.arthro.2023.12.011. Epub 2024 Feb 27.
To compare clinical outcomes, knee stability and complications, failure, and revision rates after anterior cruciate ligament repair (ACLr) with dynamic intraligamentary stabilization (DIS) versus anterior cruciate ligament reconstruction (ACLR) with hamstring autograft for primary ACL ruptures at short and mid-term follow-up.
A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review of PubMed/MEDLINE and Scopus was performed. Studies that evaluated patients undergoing ACLr with DIS or ACLR with hamstring autograft were considered for inclusion. Studies were excluded if patients were affected by concomitant meniscal, ligamentous, or chondral injuries needing surgical treatment, because of their potential confounding effect on postoperative outcomes. The Risk of Bias-2 tool was used to assess the risk of bias in the included studies. The quality of available evidence was rated according to Grading of Recommendations Assessment, Development, and Evaluation recommendations. The study protocol was registered in the PROSPERO database (ID: CRD42023394558).
Five randomized controlled trials comparing the outcomes of ACLr with DIS versus ACLR with hamstring autograft met the inclusion criteria. No major differences in terms of patient-reported outcomes (International Knee Documentation Committee subjective form, Lysholm score, Tegner activity scale, Knee injury and Osteoarthritis Outcome Score, visual analog scale satisfaction) or rates of complications, revisions, and failures were found in included studies at all time points. Repair showed greater International Knee Documentation Committee subjective form scores at 5 years in one study, whereas ACLR displayed significantly increased knee stability at 6 months and 5 years in 2 different studies, although the clinical relevance of these differences is doubtful.
The results of this study suggest that ACLr with DIS is not inferior to ACLR with hamstring autograft in terms of rates of clinical outcomes, knee stability, risk of failure, complications, and revision surgery. Therefore, ACLr with DIS may be a viable alternative to ACLR with hamstring autograft in selected patients.
Level I, systematic review of Level I studies.
比较原发性前交叉韧带(ACL)撕裂患者接受动态关节内韧带稳定术(DIS)与自体腘绳肌腱前交叉韧带重建术(ACLR)的短期和中期临床结果、膝关节稳定性、并发症、失败率和翻修率。
对 PubMed/MEDLINE 和 Scopus 进行了符合系统评价和荟萃分析首选报告项目的系统综述。纳入评估接受 DIS 或 ACLR 联合自体腘绳肌腱治疗的 ACL 患者的研究。如果患者同时存在需要手术治疗的半月板、韧带或软骨损伤,由于这些损伤可能对术后结果产生混杂影响,则排除这些研究。采用偏倚风险评估工具 2(Risk of Bias-2)评估纳入研究的偏倚风险。根据推荐评估、制定与评价(Grading of Recommendations Assessment, Development, and Evaluation)建议对可用证据质量进行分级。研究方案在 PROSPERO 数据库中进行了注册(ID:CRD42023394558)。
纳入的 5 项随机对照试验比较了 DIS 与 ACLR 联合自体腘绳肌腱治疗的结果。在所有时间点,纳入研究均未发现患者报告的结局(国际膝关节文献委员会主观评分、Lysholm 评分、Tegner 活动量表、膝关节损伤和骨关节炎结果评分、视觉模拟评分满意度)或并发症、翻修和失败率存在显著差异。在一项研究中,5 年时修复组的国际膝关节文献委员会主观评分更高,而在另外两项研究中,6 个月和 5 年时 ACLR 组的膝关节稳定性显著增加,尽管这些差异的临床相关性值得怀疑。
本研究结果表明,在临床结局、膝关节稳定性、失败风险、并发症和翻修手术方面,DIS 与 ACLR 联合自体腘绳肌腱治疗并无差异。因此,在选择患者时,DIS 与 ACLR 联合自体腘绳肌腱治疗可能是一种可行的替代方案。
I 级,对 I 级研究的系统综述。