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慢性阻塞性肺疾病和哮喘患者远程监测与传统护理的真实世界比较:对临床结局和患者特征的影响:回顾性队列研究。

Real-World Comparison of Telemonitoring Versus Conventional Care in Patients With Chronic Obstructive Pulmonary Disease and Those With Asthma-Impact on Clinical Outcomes and Patient Characteristics: Retrospective Cohort Study.

作者信息

Roubos Lidy Aaltje Catharina, Westland Heleen, Hulstein-Brink Niesje Lieset, Visser Rosalie Constance, van den Berg Jan Willem K, Leenen Jobbe Pl

机构信息

Connected Care Centre, Isala, Dr van Heesweg 2, Zwolle, 8025 AB, The Netherlands, 31 0886245000.

Nursing Sciences, Program in Clinical Health Sciences, Utrecht University, Utrecht, The Netherlands.

出版信息

J Med Internet Res. 2025 Aug 14;27:e66743. doi: 10.2196/66743.

Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) and asthma belong to the most common chronic diseases and their incidence continues to rise. Many patients experience exacerbations leading to hospitalization, impacting quality of life and straining health care systems. Telemonitoring emerged as a substitute for outpatient clinic visits, aiming to intervene early and prevent hospitalization. However, studies evaluating telemonitoring are conducted in controlled settings and may not fully reflect real-world conditions. Real-world evidence is needed to understand how telemonitoring functions in routine clinical practice.

OBJECTIVE

This study aims to describe and compare patient characteristics and clinical outcomes of patients with COPD or asthma who received telemonitoring versus conventional care based on real-world data.

METHODS

An observational cohort study with retrospective data collection was conducted with data from newly diagnosed patients with COPD or asthma who received telemonitoring or conventional care with up to 1-year follow-up. Outcomes included patient characteristics, COPD- or asthma-related hospitalizations, emergency department visits, exacerbations, and outpatient clinic visits. The telemonitoring intervention involves a mobile app where patients weekly complete the Asthma Control Questionnaire or the Clinical COPD Questionnaire, allowing nurses to intervene if scores indicate deterioration. The app serves as a substitute for outpatient clinic visits for patients with COPD, while patients with asthma use it as a complement to these visits.

RESULTS

The study included 614 patients in conventional care and 96 patients in telemonitoring. Telemonitoring users are younger, predominantly female, rarely current smokers, and have fewer comorbidities. More patients with asthma used telemonitoring than patients with COPD. Patients using telemonitoring showed more moderate exacerbations (incidence rate ratio [IRR] 2.15, 95% CI 1.16-3.98; P=.02). Although telemonitoring users experienced fewer hospitalizations, this was not significant after adjusting for confounders (IRR 0.68, 95% CI 0.15-3.11; P=.62). Telemonitoring users had more telephone and screen-to-screen consultations (IRR 7.16, 95% CI 5.47-9.36; P<.001), but outpatient clinic visits remained consistent across both groups (IRR 1.19, 95% CI 0.88-1.62; P=.27).

CONCLUSIONS

Patient characteristic differences and clinical outcome differences were identified between telemonitoring and conventional care. Although telemonitoring facilitated earlier initiation of treatment, it did not lead to fewer hospital or outpatient clinic visits. More insight is needed into factors influencing participation in telemonitoring to better serve current users and improve accessibility for nonusers. Patients should be provided with additional guidance on effectively using the communication channels offered by telemonitoring. This may encourage them to use these methods instead of attending outpatient clinic visits. Additionally, when implementing telemonitoring, it is essential to critically evaluate and redesign care processes to prevent unnecessary health care use.

摘要

背景

慢性阻塞性肺疾病(COPD)和哮喘属于最常见的慢性病,其发病率持续上升。许多患者会经历病情加重并导致住院,这影响了生活质量,也给医疗保健系统带来了压力。远程监测作为门诊就诊的替代方式应运而生,旨在早期干预并预防住院。然而,评估远程监测的研究是在受控环境中进行的,可能无法完全反映现实世界的情况。需要真实世界的证据来了解远程监测在常规临床实践中的作用。

目的

本研究旨在根据真实世界数据描述和比较接受远程监测与传统护理的慢性阻塞性肺疾病或哮喘患者的特征和临床结局。

方法

进行了一项回顾性数据收集的观察性队列研究,数据来自新诊断的慢性阻塞性肺疾病或哮喘患者,这些患者接受了远程监测或传统护理,并进行了长达1年的随访。结局包括患者特征、慢性阻塞性肺疾病或哮喘相关的住院、急诊科就诊、病情加重以及门诊就诊。远程监测干预包括一个移动应用程序,患者每周在该应用程序上完成哮喘控制问卷或慢性阻塞性肺疾病临床问卷,如果分数显示病情恶化,护士可进行干预。该应用程序替代慢性阻塞性肺疾病患者的门诊就诊,而哮喘患者则将其作为门诊就诊的补充。

结果

该研究纳入了614例接受传统护理的患者和96例接受远程监测的患者。使用远程监测的患者更年轻,女性居多,目前吸烟者较少,合并症也较少。使用远程监测的哮喘患者比慢性阻塞性肺疾病患者更多。使用远程监测的患者出现更多中度病情加重(发病率比[IRR] 2.15,95%可信区间1.16 - 3.98;P = 0.02)。尽管使用远程监测的患者住院次数较少,但在调整混杂因素后这一差异不显著(IRR 0.68,95%可信区间0.15 - 3.11;P = 0.62)。使用远程监测的患者有更多的电话和视频会诊(IRR 7.16,95%可信区间5.47 - 9.36;P < 0.001),但两组的门诊就诊次数保持一致(IRR 1.19,95%可信区间0.88 - 1.62;P = 0.27)。

结论

在远程监测和传统护理之间发现了患者特征差异和临床结局差异。尽管远程监测有助于更早开始治疗,但并未减少住院或门诊就诊次数。需要更深入了解影响参与远程监测的因素,以便更好地服务当前用户并提高非用户的可及性。应向患者提供关于有效使用远程监测提供的沟通渠道的额外指导。这可能会鼓励他们使用这些方法而非前往门诊就诊。此外,在实施远程监测时,必须严格评估和重新设计护理流程,以防止不必要的医疗保健使用。

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