Afolabi Jacob Babatunde, Oziegbe Elizabeth Obhioneh, Adegoke Samuel Ademola, Adefehinti Olufemi, Oyetola Elijah Olufemi, Foláyan Moréniké Oluwátóyìn
Department of Child Dental Health, Obafemi Awolowo University Teaching Hospitals' Complex, Ile-Ife, Nigeria.
Department of Child Dental Health, Faculty of Dentistry, Obafemi Awolowo University, Ile-Ife, Nigeria.
BMC Res Notes. 2025 Aug 14;18(1):353. doi: 10.1186/s13104-025-07418-6.
The cascade of events in children with sickle cell anaemia (SCA) may influence their caries experience. This case-control study aimed to compare the dental caries prevention profile (captured via caries experience, risk behaviours, and access patterns) of the primary and permanent dentitions of children with and without SCA in a suburban community in Nigeria.
This is a sub-study of a larger case-control study that recruited 264 children (120 males, 144 females; mean age 9.41 ± 3.35 years). Among those with primary dentition (n = 207), 13.5% had dental caries. Children with SCA had twice the dental caries experience as those without (17.9% vs. 8.9%), though not statistically significant (p = 0.06). No significant associations were found between caries and tooth brushing, daily fluoride use, or frequency of daily consumption of refined carbohydrates. However, caries was significantly higher among children who had used dental services (50% vs. 10.9%; p < 0.001). The dmft score was significantly higher in children with SCA (p = 0.04) and girls (p = 0.02). In permanent teeth, children with SCA with fair hygiene had higher DMFT scores (p = 0.03).
Not applicable.
镰状细胞贫血（SCA）患儿发生的一系列事件可能会影响他们的龋齿患病情况。这项病例对照研究旨在比较尼日利亚一个郊区社区中患和未患SCA的儿童乳牙列和恒牙列的龋齿预防情况（通过龋齿患病情况、风险行为和就诊模式来体现）。
这是一项更大规模病例对照研究的子研究，该研究招募了264名儿童（120名男性，144名女性；平均年龄9.41±3.35岁）。在乳牙列儿童（n = 207）中，13.5%患有龋齿。患SCA的儿童龋齿患病几率是未患SCA儿童的两倍（17.9%对8.9%），但差异无统计学意义（p = 0.06）。龋齿与刷牙、每日使用氟化物或每日食用精制碳水化合物的频率之间未发现显著关联。然而，看过牙科的儿童龋齿患病率显著更高（50%对10.9%；p < 0.001）。患SCA的儿童（p = 0.04）和女孩（p = 0.02）的乳牙龋失补牙面（dmft）评分显著更高。在恒牙列中，口腔卫生一般的患SCA儿童的恒牙龋失补牙面（DMFT）评分更高（p = 0.03）。
不适用。
