Hess H J, Bindra J S, Constantine J W, Elger W, Loge O, Schillinger E, Losert W
Experientia. 1977 Aug 15;33(8):1076-7. doi: 10.1007/BF01945979.
N-methanesulfonyl 16-phenoxy-omega-tetranor PGE2 is a prostaglandin analog which is markedly more tissue selective than PGE2. This compound is 10-30 times more potent than PGE2 in animal models which are considered relevant to antifertility effects in humans. In pharmacological tests which are believed to be predictive for side effects in humans, the compound has potency either equal to or less than that of PGE2.
N-甲磺酰基16-苯氧基-ω-四降前列腺素E2是一种前列腺素类似物，其组织选择性明显高于前列腺素E2。在被认为与人类抗生育作用相关的动物模型中，该化合物的效力比前列腺素E2强10至30倍。在被认为可预测人类副作用的药理试验中，该化合物的效力等于或低于前列腺素E2。
