Losin Ilya, Assali Abid, Pereg David, Arow Ziad, Giladi Ela, Hilu Ranin, Omelchenko Alexander
Cardiology Department, Meir Medical Center, Kfar Saba, Israel.
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Gerontology. 2025 Aug 18:1-6. doi: 10.1159/000547101.
Frailty is a syndrome characterized by increased vulnerability to stressful events due to diminished metabolic, neuromuscular, and functional reserves. It has been associated with poor outcomes in patients with cardiovascular diseases. This study compares the eyeball test and the Fried test (considered the "gold standard") for frailty assessment in elderly patients in an electrophysiology clinic.
This prospective study included stable patients aged 75 years and older who were assessed in an electrophysiology clinic. Frailty assessment was conducted using both the Eyeball and Fried tests. Patients were first evaluated by an electrophysiologist who used the Eyeball test to grade frailty on a Fried-type scale (1-5, with frailty defined as a score ≥3). Subsequently, each patient underwent objective measurements of frailty using the Fried test.
A total of 201 patients with a median age of 82 ± 7 years were included in the study, with 62% being males. According to the Fried test, 81 (40%) patients were classified as frail. The majority of frail patients were over 80 years old. The eyeball test demonstrated an 88.9% sensitivity and a 78.3% specificity in diagnosing frailty. Accordingly, positive and negative predictive values were 73.5% and 91.2%, respectively.
The eyeball test is highly accurate for ruling out frailty in elderly outpatients in an electrophysiology clinic. However, when frailty is suspected based on the eyeball test, an additional objective test, such as the Fried test, should be used to confirm the diagnosis.
衰弱是一种综合征,其特征是由于代谢、神经肌肉和功能储备减少,对压力事件的易感性增加。它与心血管疾病患者的不良预后相关。本研究比较了眼球测试和弗里德测试(被认为是“金标准”)在电生理门诊老年患者衰弱评估中的应用。
这项前瞻性研究纳入了在电生理门诊接受评估的75岁及以上的稳定患者。使用眼球测试和弗里德测试进行衰弱评估。患者首先由电生理学家进行评估,电生理学家使用眼球测试按照弗里德类型量表对衰弱进行分级(1 - 5级,衰弱定义为得分≥3)。随后,每位患者使用弗里德测试进行衰弱的客观测量。
本研究共纳入201例患者,中位年龄为82±7岁,其中62%为男性。根据弗里德测试,81例(40%)患者被分类为衰弱。大多数衰弱患者年龄超过80岁。眼球测试在诊断衰弱方面显示出88.9%的敏感性和78.3%的特异性。相应地,阳性预测值和阴性预测值分别为73.5%和91.2%。
眼球测试在排除电生理门诊老年门诊患者的衰弱方面具有高度准确性。然而,当基于眼球测试怀疑存在衰弱时,应使用额外的客观测试,如弗里德测试,来确诊。