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新生儿自发性胃穿孔:一例报告

Spontaneous Neonatal Gastric Perforation: A Case Report.

作者信息

Azirar Abir, Ech-Chebab Mohammed, Ayyad Anass, Messaoudi Sahar, Benhaddou Houssain, Amrani Rim

机构信息

Department of Pediatrics, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Mohammed First University of Oujda, Oujda, MAR.

Department of Neonatology and Neonatal Intensive Care, Mohammed VI University Hospital, Oujda, MAR.

出版信息

Cureus. 2025 Jul 14;17(7):e87877. doi: 10.7759/cureus.87877. eCollection 2025 Jul.

DOI:10.7759/cureus.87877
PMID:40821189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12351511/
Abstract

Spontaneous gastric perforation (SGP) is a rare but life-threatening surgical emergency in neonates, particularly among preterm infants. We report the case of a male neonate born at 33 weeks of gestation via spontaneous vaginal delivery, with a birth weight of 1,780 grams. The initial postnatal adaptation was satisfactory. However, on the second day of life, the infant developed sudden and severe abdominal distension associated with bilious vomiting and signs of respiratory distress. A plain abdominal radiograph revealed a massive pneumoperitoneum, highly suggestive of gastrointestinal perforation. The neonate underwent emergency exploratory laparotomy, which revealed a 2 cm linear perforation on the anterior wall of the stomach. The perforation was repaired primarily without the need for gastric resection. Despite early surgical intervention and aggressive postoperative management in a neonatal intensive care unit, the infant's condition deteriorated rapidly. He developed signs of sepsis, refractory shock, and multiorgan failure, and succumbed within 48 hours postoperatively. This case underscores the fulminant course and high mortality rate associated with SGP, especially in preterm neonates. It highlights the critical importance of maintaining a high index of suspicion in the presence of acute abdominal symptoms and radiologic findings, as early diagnosis and prompt surgical intervention are essential for improving outcomes in these vulnerable patients.

摘要

自发性胃穿孔(SGP)是新生儿中一种罕见但危及生命的外科急症,在早产儿中尤为常见。我们报告一例孕33周经自然阴道分娩的男婴,出生体重1780克。出生后最初的适应情况良好。然而,在出生后第二天,婴儿突然出现严重腹胀,伴有胆汁性呕吐和呼吸窘迫体征。腹部平片显示大量气腹,高度提示胃肠道穿孔。该新生儿接受了急诊剖腹探查术,术中发现胃前壁有一个2厘米的线性穿孔。穿孔主要通过修补而无需胃切除。尽管早期进行了手术干预并在新生儿重症监护病房进行了积极的术后管理,但婴儿的病情迅速恶化。他出现了败血症、难治性休克和多器官功能衰竭的体征,并在术后48小时内死亡。该病例强调了SGP的暴发性病程和高死亡率,尤其是在早产新生儿中。它突出了在出现急性腹部症状和影像学表现时保持高度怀疑的至关重要性,因为早期诊断和及时的手术干预对于改善这些脆弱患者的预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/42e4b34d9b55/cureus-0017-00000087877-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/7dd84437cad3/cureus-0017-00000087877-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/fc57b42cdec3/cureus-0017-00000087877-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/9501510a1d23/cureus-0017-00000087877-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/42e4b34d9b55/cureus-0017-00000087877-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/7dd84437cad3/cureus-0017-00000087877-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/fc57b42cdec3/cureus-0017-00000087877-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/9501510a1d23/cureus-0017-00000087877-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece3/12351511/42e4b34d9b55/cureus-0017-00000087877-i04.jpg

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