Assefa Gobezu, Makuach Bhan, Tabor Biniyam Beyene, Hailu Samuel Sisay
Gambella Town Primary Hospital Gambella, Ethiopia.
Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, USA.
Ann Med Surg (Lond). 2025 May 30;87(7):4672-4675. doi: 10.1097/MS9.0000000000003443. eCollection 2025 Jul.
Spontaneous gastric perforation is a rare yet life-threatening condition, particularly in children beyond the neonatal period. While relatively common in neonates and occasionally seen in adults, its occurrence in older children is rare and often lacks identifiable causes.
We report the case of a 6-year-old child who presented with acute abdominal distension and severe pain. Radiographic evaluation revealed pneumoperitoneum, indicative of viscus perforation. During the surgical exploration, a round perforation was identified at the prepyloric region. A pathological examination confirmed ischemic changes at the perforation site. The patient had no history of trauma, medication use, or ingestion of toxic substances and testing was negative.
Spontaneous gastric perforation beyond the neonatal period is uncommon. Studies suggested that gastric wall ischemia plays a role in the pathophysiology of gastric wall perforation. In one case series, pathological evaluation of five cases revealed transmural necrosis of the gastric wall. This case supplements the cohort potentially providing new insights into the etiology.
This case underscores the rarity of spontaneous gastric perforation in preschool-aged children and highlights the importance of its inclusion as a differential diagnosis in pediatric acute abdomen. Early diagnosis through clinical and radiographic assessments, followed by timely surgical intervention, is critical for reducing mortality. This report contributes to the limited literature on this condition and emphasizes the need for a high index of clinical and radiological suspicion to ensure prompt management.
自发性胃穿孔是一种罕见但危及生命的病症,尤其在新生儿期后的儿童中。虽然在新生儿中相对常见,在成人中偶尔可见,但在大龄儿童中其发生较为罕见,且往往缺乏可明确的病因。
我们报告一例6岁儿童,其表现为急性腹胀和剧痛。影像学评估显示存在气腹,提示脏器穿孔。在手术探查过程中,于幽门前区域发现一个圆形穿孔。病理检查证实穿孔部位存在缺血性改变。该患者无外伤史、用药史或有毒物质摄入史,检测结果为阴性。
新生儿期后的自发性胃穿孔并不常见。研究表明胃壁缺血在胃壁穿孔的病理生理过程中起作用。在一个病例系列中,对5例病例的病理评估显示胃壁全层坏死。本病例补充了该病例组,可能为病因学提供新的见解。
本病例强调了学龄前儿童自发性胃穿孔的罕见性,并突出了将其纳入小儿急腹症鉴别诊断的重要性。通过临床和影像学评估进行早期诊断,随后及时进行手术干预,对于降低死亡率至关重要。本报告为关于这种病症的有限文献做出了贡献,并强调需要高度的临床和放射学怀疑指数以确保及时处理。