Alabrahim Obaydah Abd Alkader, Abdeldayem Ahmed Maher, Azzazy Hassan Mohamed El-Said
Department of Chemistry, School of Sciences & Engineering, The American University in Cairo AUC Avenue, SSE # 1184, P. O. Box 74 New Cairo 11835 Egypt
Department of Nanobiophotonics, Leibniz Institute of Photonic Technology Albert Einstein Str. 9 Jena 07745 Germany.
Nanoscale Adv. 2025 Jul 24. doi: 10.1039/d5na00644a.
Plant extracts, rich in bioactive compounds such as phenolics and flavonoids, serve as reducing and stabilizing agents in nanoparticles fabrication. The genus, comprising species like , , and , has demonstrated significant potential in synthesizing metallic nanoparticles with enhanced physicochemical and biomedical properties. This review provides a comprehensive description of the phytochemical composition of different species and their utilization in nanoparticles synthesis. It further explores the biological mechanisms underlying their antimicrobial, antioxidant, anti-inflammatory, and anticancer activities, along with their safety and stability profiles. The review highlights the promise of -derived metallic nanoparticles in biomedical applications, while emphasizing mechanistic, toxicological, and stability considerations crucial for clinical translation.
富含酚类和黄酮类等生物活性化合物的植物提取物，在纳米颗粒制备中用作还原剂和稳定剂。该属包括[具体物种1]、[具体物种2]和[具体物种3]等物种，已显示出在合成具有增强物理化学和生物医学特性的金属纳米颗粒方面具有巨大潜力。本综述全面描述了不同[该属物种]的植物化学成分及其在纳米颗粒合成中的应用。它进一步探讨了其抗菌、抗氧化、抗炎和抗癌活性背后的生物学机制，以及它们的安全性和稳定性概况。该综述强调了源自[该属物种]的金属纳米颗粒在生物医学应用中的前景，同时强调了对临床转化至关重要的机制、毒理学和稳定性考虑因素。
