在黑腹果蝇中，一组与性染色体异染色质相互作用的紧密连锁常染色体基因的证据。
Evidence for a set of closely linked autosomal genes that interact with sex-chromosome heterochromatin in Drosophila melanogaster.
作者信息
Sandler L
出版信息
Genetics. 1977 Jul;86(3):567-82. doi: 10.1093/genetics/86.3.567.
Abstract
It is proposed that there exists a special region in the euchromatin of the left arm of chromosome 2 (contained within sections 31-32 of the standard salivary gland chromosome map) that is defined by a set of genes, each one of which interacts with a specific sex-chromosome heterochromatic segment. The evidence for the existence of this region is, first, the exhibition, mapping, and analysis of five different maternal-effect, embryonic semi-lethals located in region 31-32. Secondly, in each case the consequence of the maternal effect is markedly influenced by the amount of X- or Y-chromosome heterochromatin carried by the progeny of mutant mothers. The nature of this interaction and possible reasons for the existence of the cluster of autosomal genes are discussed.
摘要
有人提出，在2号染色体左臂的常染色质中存在一个特殊区域（包含在标准唾液腺染色体图谱的31-32节内），该区域由一组基因定义，其中每个基因都与一个特定的性染色体异染色质区段相互作用。该区域存在的证据如下：首先，对位于31-32区域的五个不同的母体效应胚胎半致死基因进行了展示、定位和分析。其次，在每种情况下，母体效应的结果都受到突变母体后代所携带的X或Y染色体异染色质数量的显著影响。本文讨论了这种相互作用的性质以及常染色体基因簇存在的可能原因。
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