黑腹果蝇突变异常卵母细胞及其与核糖体DNA相互作用的研究。
Studies on the mutation abnormal oocyte and its interaction with the ribosomal DNA of Drosophila melanogaster.
作者信息
Krider H M, Levine B I
出版信息
Genetics. 1975 Nov;81(3):501-13. doi: 10.1093/genetics/81.3.501.
Abstract
Sandler (1970) suggested that mutation, abnormal oocyte (abo:2-38), may influence the function of the ribosomal RNA cistrons. We have examined the abo mutation and its interaction with the ribosomal DNA of Drosophila melanogaster. We observed that the expression of the abo phenotype is unstable under the appropriate conditions, a behavior which paralleled changes in the phenotypic expression of bobbed mutations during the magnification of the ribosomal DNA. The change in the expression of the abo phenotype is correlated with an increase in the redundancy of the ribosomal cistrons, further suggesting a functional interaction of the abo and bobbed regions.
摘要
桑德勒（1970年）提出，突变，即异常卵母细胞（abo:2 - 38），可能会影响核糖体RNA顺反子的功能。我们已经研究了abo突变及其与黑腹果蝇核糖体DNA的相互作用。我们观察到，在适当条件下，abo表型的表达是不稳定的，这种行为与核糖体DNA扩增过程中截短突变表型表达的变化相似。abo表型表达的变化与核糖体顺反子冗余度的增加相关，这进一步表明abo区域和截短区域之间存在功能相互作用。
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