高剂量8%辣椒素贴剂治疗孕妇慢性神经性背痛：一例报告
High-Dose 8% Capsaicin Patch in Treatment of Chronic Neuropathic Back Pain in a Pregnant Woman: A Case Report.
作者信息
Oh Seung Mi, Diaz Yerissa A, Stilli Ludovica, Slinchenkova Kateryna, Gritsenko Karina, Vydyanathan Amaresh, Breidenbach Kathryn, Borowski Blaze, Koushik Sarang S, Viswanath Omar, Shaparin Naum
机构信息
Anesthesiology Montefiore Medical Center.
Anesthesiology Albert Einstein College of Medicine.
出版信息
Orthop Rev (Pavia). 2025 Jun 16;17:140712. doi: 10.52965/001c.140712. eCollection 2025.
INTRODUCTION
Managing pain during pregnancy is challenging due to fetus safety and limited data on perinatal pain treatments. We report the first successful management of neuropathic back pain with high dose 8% Capsaicin patches (Qutenza) in a pregnant patient who failed other modalities.
CASE PRESENTATION
A 34-year-old female with a history of migraines, childhood scoliosis status-post T5-L3 posterior spinal fusion complicated by post-laminectomy syndrome, presented with myofascial and neuropathic back pain. Her pain was refractory to oral agents, injections, field stimulator, and partial surgical revision. During patch treatments, she became pregnant.
MANAGEMENT AND OUTCOMES
A review of the patient's record and consent were obtained. Trial of an 8% capsaicin patch provided significant relief of her pain twice. Following OB/GYN consultation, she continued patch treatment, achieving significant relief without pregnancy complications into a subsequent pregnancy.
CONCLUSION
Following further study, 8% capsaicin patches may be suitable alternatives for pain management during pregnancy.
引言
由于胎儿安全以及围产期疼痛治疗方面的数据有限，孕期疼痛管理具有挑战性。我们报告了首例成功使用高剂量8%辣椒素贴剂（Qutenza）治疗一名其他治疗方式均失败的孕妇神经性背痛的案例。
病例介绍
一名34岁女性，有偏头痛病史，儿童期脊柱侧弯，曾行T5-L3后路脊柱融合术，术后并发椎板切除术后综合征，出现肌筋膜性和神经性背痛。她的疼痛对口服药物、注射、场刺激器及部分手术翻修均无效。在进行贴剂治疗期间，她怀孕了。
治疗与结果
查阅了患者病历并获得了同意。试用8%辣椒素贴剂两次均显著缓解了她的疼痛。经妇产科会诊后，她继续进行贴剂治疗，在后续妊娠中疼痛得到显著缓解且未出现妊娠并发症。
结论
经过进一步研究，8%辣椒素贴剂可能是孕期疼痛管理的合适替代方法。
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