• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

疑似侵袭性膀胱癌继发尿液性化学性腹膜炎：一例报告

Suspected Urine-Induced Chemical Peritonitis Secondary to Invasive Bladder Cancer: A Case Report.

作者信息

Szymkiewicz Stanislaw

机构信息

Department of Urology, Janusz Korczak Provincial Specialist Hospital, Slupsk, POL.

出版信息

Cureus. 2025 Aug 14;17(8):e90092. doi: 10.7759/cureus.90092. eCollection 2025 Aug.

DOI:10.7759/cureus.90092
PMID:40823461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12352707/
Abstract

Chemical (urine-induced) peritonitis is a rare but potentially life-threatening complication in patients with advanced bladder cancer. It may result from sterile urinary leakage into the peritoneal cavity, typically through microscopic wall disruption or tumor necrosis. This condition can mimic perforation or bacterial peritonitis, posing a significant diagnostic challenge. We describe the case of a 78-year-old male with de novo high-grade urothelial carcinoma, presenting with persistent gross hematuria, bilateral hydronephrosis, and severe anemia. Despite initial tumor resection and nephrostomy placement, the patient's condition deteriorated with signs of peritoneal irritation and systemic inflammation. Emergency cystoprostatectomy revealed extensive tumor necrosis and inflammatory peritoneal fluid, but no macroscopic bladder perforation. Histopathology confirmed muscle-invasive high-grade urothelial carcinoma (pT2b) with necrosis and angioinvasion. This report illustrates a diagnostic and therapeutic challenge in the management of advanced bladder cancer complicated by suspected sterile chemical peritonitis, emphasizing the importance of early source control in critically ill patients.

摘要

化学性（尿液诱发的）腹膜炎是晚期膀胱癌患者中一种罕见但可能危及生命的并发症。它可能源于无菌性尿液漏入腹腔，通常是通过微小的膀胱壁破裂或肿瘤坏死。这种情况可类似穿孔或细菌性腹膜炎，带来重大的诊断挑战。我们描述了一名78岁男性患者的病例，该患者患有新发高级别尿路上皮癌，表现为持续性肉眼血尿、双侧肾积水和严重贫血。尽管最初进行了肿瘤切除和肾造瘘术，但患者病情恶化，出现了腹膜刺激征和全身炎症表现。急诊膀胱前列腺切除术显示广泛的肿瘤坏死和炎性腹腔积液，但未见肉眼可见的膀胱穿孔。组织病理学证实为肌层浸润性高级别尿路上皮癌（pT2b）伴坏死和血管侵犯。本报告说明了在疑似无菌性化学性腹膜炎并发的晚期膀胱癌管理中的诊断和治疗挑战，强调了在危重症患者中早期源头控制的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/74a00ce2ffa5/cureus-0017-00000090092-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/193199652f95/cureus-0017-00000090092-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/423f54298596/cureus-0017-00000090092-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/758a4d0494d4/cureus-0017-00000090092-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/8aaa486d85f7/cureus-0017-00000090092-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/74a00ce2ffa5/cureus-0017-00000090092-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/193199652f95/cureus-0017-00000090092-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/423f54298596/cureus-0017-00000090092-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/758a4d0494d4/cureus-0017-00000090092-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/8aaa486d85f7/cureus-0017-00000090092-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db2e/12352707/74a00ce2ffa5/cureus-0017-00000090092-i05.jpg

相似文献

1
Suspected Urine-Induced Chemical Peritonitis Secondary to Invasive Bladder Cancer: A Case Report.疑似侵袭性膀胱癌继发尿液性化学性腹膜炎：一例报告
Cureus. 2025 Aug 14;17(8):e90092. doi: 10.7759/cureus.90092. eCollection 2025 Aug.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方：益处与风险
3
Silent but Invasive: A Case Report of a Sarcomatoid Bladder Carcinoma in a 29-Year-Old Male Presenting As Vesico-Cutaneous Fistula Without Hematuria.隐匿却具侵袭性：一名29岁男性膀胱肉瘤样癌病例报告，表现为膀胱皮肤瘘且无血尿
Cureus. 2025 Jul 18;17(7):e88261. doi: 10.7759/cureus.88261. eCollection 2025 Jul.
4
Ophthalmia Neonatorum新生儿眼炎
5
Progressive Multiple Sclerosis Presenting With Obstructive Uropathy and Acute Kidney Injury: A Case Report.以梗阻性尿病和急性肾损伤为表现的进展性多发性硬化症：一例报告
Cureus. 2025 Aug 8;17(8):e89643. doi: 10.7759/cureus.89643. eCollection 2025 Aug.
6
Immunotherapy for advanced or metastatic urothelial carcinoma.晚期或转移性尿路上皮癌的免疫治疗。
Cochrane Database Syst Rev. 2023 Oct 9;10(10):CD013774. doi: 10.1002/14651858.CD013774.pub2.
7
Systemic Inflammatory Response Syndrome全身炎症反应综合征
8
Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms: FUTURE, a superiority RCT and economic evaluation.侵入性尿动力学检查在难治性膀胱过度活动症女性患者管理中的应用：FUTURE，一项优效性随机对照试验及经济学评估
Health Technol Assess. 2025 Jul;29(27):1-139. doi: 10.3310/UKYW4923.
9
Topical versus systemic antibiotics for chronic suppurative otitis media.用于慢性化脓性中耳炎的局部用抗生素与全身用抗生素对比
Cochrane Database Syst Rev. 2025 Jun 9;6(6):CD013053. doi: 10.1002/14651858.CD013053.pub3.
10
Management of urinary stones by experts in stone disease (ESD 2025).结石病专家对尿路结石的管理（2025年结石病专家共识）
Arch Ital Urol Androl. 2025 Jun 30;97(2):14085. doi: 10.4081/aiua.2025.14085.

本文引用的文献

1
Bladder rupture secondary to bladder tumors: A gateway to peritoneal carcinoma ?膀胱肿瘤继发膀胱破裂：通向腹膜癌的途径？
Urol Case Rep. 2024 Jun 12;55:102767. doi: 10.1016/j.eucr.2024.102767. eCollection 2024 Jul.
2
A Huge Hemangioma of the Urinary Bladder: A Case Report and Literature Review.膀胱巨大血管瘤：病例报告及文献综述
Cureus. 2024 Jan 24;16(1):e52852. doi: 10.7759/cureus.52852. eCollection 2024 Jan.
3
The Role of Imaging in Bladder Cancer Diagnosis and Staging.影像学在膀胱癌诊断和分期中的作用。
Diagnostics (Basel). 2020 Sep 16;10(9):703. doi: 10.3390/diagnostics10090703.
4
Spontaneous Rupture of Bladder : A Rare Clinical Entity.膀胱自发性破裂：一种罕见的临床病症。
Med J Armed Forces India. 2007 Jan;63(1):92-3. doi: 10.1016/S0377-1237(07)80126-2. Epub 2011 Jul 21.
5
The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part B: Prostate and Bladder Tumours.《2016 年世界卫生组织泌尿系统及男性生殖器官肿瘤分类-第 B 部分：前列腺和膀胱肿瘤》。
Eur Urol. 2016 Jul;70(1):106-119. doi: 10.1016/j.eururo.2016.02.028. Epub 2016 Mar 17.
6
Risk factors for mortality and morbidity related to radical cystectomy.根治性膀胱切除术相关的死亡率和发病率的危险因素。
BJU Int. 2009 Jan;103(2):191-6. doi: 10.1111/j.1464-410X.2008.07889.x. Epub 2008 Jul 29.
7
Radiographic and clinical predictors of bladder rupture in blunt trauma patients with pelvic fracture.骨盆骨折钝性创伤患者膀胱破裂的影像学和临床预测因素
Acad Radiol. 2006 May;13(5):573-9. doi: 10.1016/j.acra.2005.10.012.
8
Carcinoma urinary bladder presenting as acute abdomen.以急腹症为表现的膀胱癌
Int Urol Nephrol. 2001;33(3):491-2. doi: 10.1023/a:1019542007777.
9
Spontaneous intraperitoneal rupture of the bladder.膀胱自发性腹膜内破裂
Urol Int. 1987;42(6):467-9. doi: 10.1159/000282019.