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急性早幼粒细胞白血病合并脑出血患者神经保护策略的探索

Exploration of neuroprotective strategies in patients with acute promyelocytic leukemia complicated by cerebral hemorrhage.

作者信息

Hu Jing, Lai Wentao

机构信息

Department of Hematology, Ganzhou People's Hospital, Ganzhou, China.

Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, China.

出版信息

Front Med (Lausanne). 2025 Jul 31;12:1597070. doi: 10.3389/fmed.2025.1597070. eCollection 2025.

Abstract

Acute promyelocytic leukemia (APL) is a highly lethal hematological malignancy associated with various complications, among which cerebral hemorrhage is one of the most severe. Implementing effective neuroprotective strategies for APL patients experiencing cerebral hemorrhage is crucial. This article aims to explore the application of neuroprotective strategies in these patients, analyzing their mechanisms, clinical efficacy, and future research directions. By reviewing existing literature, we reveal the potential of neuroprotective strategies to improve prognosis, reduce neurological damage, and promote recovery, thereby providing guidance for clinical practice.

摘要

急性早幼粒细胞白血病(APL)是一种与多种并发症相关的高度致命性血液系统恶性肿瘤,其中脑出血是最严重的并发症之一。为发生脑出血的APL患者实施有效的神经保护策略至关重要。本文旨在探讨神经保护策略在这些患者中的应用,分析其机制、临床疗效及未来研究方向。通过回顾现有文献,我们揭示了神经保护策略在改善预后、减少神经损伤和促进恢复方面的潜力,从而为临床实践提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de65/12350354/cce0ea0a48a5/fmed-12-1597070-g001.jpg

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