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超越针头:临床医生的专业技能如何影响半面痉挛的治疗结果。

Beyond the needle: how clinician expertise affects outcomes in the treatment of hemifacial spasm.

作者信息

Luque-Llano Melissa, Angelica-Coronel Maria, Alvarado-Vanegas Yulexy T, Puello Floralinda García, Ortega Laura Arzuza, Vincos Gustavo B

机构信息

Department of Neurology Universidad Simón Bolívar, Health sciences faculty, Barranquilla 080001, Colombia.

Universidad Simón Bolívar, Health Sciences Faculty, Barranquilla 080001, Colombia.

出版信息

Clin Park Relat Disord. 2025 Aug 6;13:100383. doi: 10.1016/j.prdoa.2025.100383. eCollection 2025.

Abstract

BACKGROUND

Hemifacial spasm (HFS) is characterized by abnormal contraction of the muscles innervated by the seventh cranial nerve. It is usually benign and diagnosed clinically. The effectiveness of botulinum toxin (BoNT) for its treatment has been well demonstrated. However, adverse events (AEs) resulting from its administration remain a concern, and some patients express reluctance to be treated by resident physicians, even when under expert supervision.

OBJECTIVE

To determine the association between the level of expertise of the neurology professional and the presence of AEs following BoNT administration in patients with HFS.

METHODS

A cross-sectional descriptive study with an analytical phase conducted at Hospital Occidente de Kennedy (Bogotá, Colombia). Out of 88 medical records reviewed, 73 met all inclusion criteria. Data analysis was performed using SPSS software version 22.

RESULTS

A predominance of female patients was observed, accounting for 74 % of the study population. The mean age of symptom onset was 54.5 ± 12.7 years, with a median symptom duration of 9 years. In most cases, the left side was affected (53.4 %). The average number of botulinum toxin applications per patient was 2.6 during the study period. Adverse events occurred in 12.6 % of cases, primarily mild facial paresis (7.9 %), hematoma (2.6 %), and eyelid ptosis (2.1 %).

CONCLUSIONS

The results did not show a statistically significant association between the level of expertise and the occurrence of adverse events. The frequency of observed adverse events was similar between the groups. This suggests that the occurrence of adverse events following BoNT administration was comparable regardless of whether the procedure was performed by a neurologist or a resident under supervision.

摘要

背景

面肌痉挛(HFS)的特征是由第七对脑神经支配的肌肉出现异常收缩。它通常为良性,通过临床诊断。肉毒杆菌毒素(BoNT)治疗该病的有效性已得到充分证实。然而,其注射引起的不良事件(AE)仍是一个问题,一些患者即使在专家监督下,也不愿接受住院医师的治疗。

目的

确定神经科专业人员的专业水平与HFS患者注射BoNT后不良事件发生之间的关联。

方法

在肯尼迪西部医院(哥伦比亚波哥大)进行了一项带有分析阶段的横断面描述性研究。在审查的88份病历中,73份符合所有纳入标准。使用SPSS 22版软件进行数据分析。

结果

观察到女性患者占优势,占研究人群的74%。症状出现的平均年龄为54.5±12.7岁,症状持续时间中位数为9年。在大多数情况下,左侧受累(53.4%)。在研究期间,每位患者肉毒杆菌毒素的平均注射次数为2.6次。12.6%的病例发生了不良事件,主要是轻度面部轻瘫(7.9%)、血肿(2.6%)和眼睑下垂(2.1%)。

结论

结果未显示专业水平与不良事件发生之间存在统计学上的显著关联。各组观察到的不良事件发生率相似。这表明,无论手术是由神经科医生还是在监督下的住院医师进行,注射BoNT后不良事件的发生情况相当。

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