Kolkailah Ahmed A, Abougergi Marwan S, Desai Parth V, Patel Axi, Fugar Setri, Okoh Alexis K, Al-Ogaili Ahmed, Hirji Sameer A, Kaneko Tsuyoshi, Volgman Annabelle Santos, Doukky Rami, Grodin Justin L, McGuire Darren K
Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, United States of America.
Parkland Health and Hospital System, Dallas, TX, United States of America.
Am Heart J Plus. 2022 Jan;13. doi: 10.1016/j.ahjo.2021.100072. Epub 2021 Nov 27.
The "July effect" refers to the potential of adverse clinical outcomes related to the annual turnover of trainees. We investigated whether this impacts inpatient heart failure (HF) outcomes.
Data from all adults (≥18 years) admitted with a primary diagnosis of HF at US teaching hospitals from the 2012-2014 National Inpatient Sample were analyzed. Non-teaching hospital admissions were excluded. The primary outcome was in-hospital mortality. Secondary metrics included hospital length of stay (LOS) and total cost adjusted for inflation. Logistic and linear regression models were used to adjust for confounders. Admissions were classified into 4 quarters (Q1-Q4), based on the academic calendar. Q1 and Q4 were designated to assess the effect of novice (July effect) versus experienced trainees, respectively.
There were 699,675 HF admissions during Q1 and Q4 in the study period. Mean age was 71 ± 15 years and 48% were females. There were 20,270 in-hospital deaths, with no difference between Q1 and Q4; crude odds ratio (OR) 1.00, 95% confidence interval (CI) 0.94-1.07, p = 0.95. After risk adjustment, there was no in-hospital mortality difference between Q1 and Q4 admissions; adjusted OR 0.96, 95% CI 0.89-1.03, p = 0.23. There was no difference in hospital LOS or total cost; 5.8 versus 5.8 days, p = 0.66 and $13,755 versus $13,586, p = 0.46, in Q1 and Q4, respectively.
In this nationally representative sample, there was no evidence of a "July effect" on inpatient HF outcomes in the US. This suggests that HF patients should not delay seeking care during trainee transitions at teaching hospitals.
“七月效应”指的是与实习生年度更替相关的不良临床结局的可能性。我们调查了这是否会影响住院心力衰竭(HF)的结局。
分析了2012 - 2014年美国教学医院全国住院样本中所有以HF为主要诊断入院的成年人(≥18岁)的数据。非教学医院的入院病例被排除。主要结局是住院死亡率。次要指标包括住院时间(LOS)和经通胀调整后的总成本。使用逻辑回归和线性回归模型来调整混杂因素。根据学术日历,入院病例被分为4个季度(Q1 - Q4)。Q1和Q4分别用于评估新手(七月效应)与经验丰富的实习生的影响。
在研究期间,Q1和Q4有699,675例HF入院病例。平均年龄为71±15岁,48%为女性。有20,270例住院死亡病例,Q1和Q4之间无差异;粗比值比(OR)为1.00,95%置信区间(CI)为0.94 - 1.07,p = 0.95。经过风险调整后,Q1和Q4入院病例的住院死亡率无差异;调整后的OR为0.96,95% CI为0.89 - 1.03,p = 0.23。住院LOS或总成本无差异;Q1和Q4分别为5.8天对5.8天,p = 0.66,以及13,755美元对13,586美元,p = 0.46。
在这个具有全国代表性的样本中,没有证据表明美国住院HF结局存在“七月效应”。这表明HF患者在教学医院实习生交接期间不应延迟寻求治疗。