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范式转变：电刺激如何在科学与医学领域开辟新途径

Paradigm shifts: how electrical stimulation opened up new avenues in science and medicine.

作者信息

Salmons Stanley

机构信息

Emeritus Professor, University of Liverpool, Liverpool.

出版信息

Eur J Transl Myol. 2025 Oct 2;35(3). doi: 10.4081/ejtm.2025.14058. Epub 2025 Aug 6.

DOI:10.4081/ejtm.2025.14058
PMID:40823968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12536683/
Abstract

The discovery that skeletal muscle can respond adaptively to use, even to the extent of re-expressing its genome, overturned two paradigms and led to new insights into gene regulation and a variety of clinical applications.

摘要

骨骼肌能够对使用情况做出适应性反应，甚至达到重新表达其基因组的程度，这一发现颠覆了两个范式，并为基因调控和多种临床应用带来了新的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/78c249e040df/ejtm-35-3-14058-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/6251631b4c87/ejtm-35-3-14058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/5ae4c2d1bdf5/ejtm-35-3-14058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/acbed195866e/ejtm-35-3-14058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/9f21d1fd6ec2/ejtm-35-3-14058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/b2b4661b8dbd/ejtm-35-3-14058-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/a37ff2bd6d9c/ejtm-35-3-14058-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/bd6eb1be02d7/ejtm-35-3-14058-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/72ba48662488/ejtm-35-3-14058-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/78c249e040df/ejtm-35-3-14058-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/6251631b4c87/ejtm-35-3-14058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/5ae4c2d1bdf5/ejtm-35-3-14058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/acbed195866e/ejtm-35-3-14058-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/9f21d1fd6ec2/ejtm-35-3-14058-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/b2b4661b8dbd/ejtm-35-3-14058-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/a37ff2bd6d9c/ejtm-35-3-14058-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/bd6eb1be02d7/ejtm-35-3-14058-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/72ba48662488/ejtm-35-3-14058-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f03a/12536683/78c249e040df/ejtm-35-3-14058-g009.jpg

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Evolution of Neuroprosthetic Approaches to Restoration of Upper Extremity Function in Spinal Cord Injury.脊髓损伤后上肢功能恢复的神经假体方法的演变
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