Wong Clarissa, Xu Perry, Ganesh Meera, Khondakar Nabila Reem, Gago Luis, Speron Dimitri, Tsai Kyle, McDonald Alyssa, Fadl-Alla Allaa, Dean Nicholas, Krambeck Amy
Department of Urology, Northwestern University, 676 N St. Clair, Suite 2300, Chicago, IL, 60611, USA.
Division of Urology, University of Alberta, Edmonton, AB, Canada.
World J Urol. 2025 Aug 18;43(1):499. doi: 10.1007/s00345-025-05871-3.
Surgery for benign prostatic hyperplasia (BPH), including holmium laser enucleation of the prostate (HoLEP), is often considered to be elective, leading to many patients waiting for intervention. Wait times for HoLEP can vary on many factors, but the incidence and impact of complications in this preoperative waiting period are unknown. We sought to uncover the outcomes of HoLEP in patients who experienced a complication while waiting for surgery.
We performed a retrospective review of a prospectively maintained database of patients who underwent HoLEP at a high-volume center between January 2021 and August 2023. Date of surgical case request placement, date of complication occurrence, and date of HoLEP were recorded. Preoperative, intraoperative, and postoperative characteristics were collected and analyzed. Statistical analysis was performed with SPSS software with p < 0.05 denoting significance.
We identified 918 patients in the database in this timeframe, with 74 experiencing a complication while waiting for HoLEP. Mean preoperative prostate volume was 122.7 ml. Complications included 8 cardiac and 37 urologic events. Complications were associated with a 31.2-day increase in wait time. Patients with cardiac complications waited 113.5 days (p = 0.013). Patients who had a complication while waiting were more likely to be on benign prostatic hyperplasia (BPH) medications, be catheter dependent, and have urinary tract infections (UTI) within 6 months of surgery. The 90-day postoperative complication rate was 31.5% in the complication group and 20.4% in the non-complication group. Patients who experienced a wait time complication were also more likely to have prolonged postoperative catheter duration and increased emergency room visits.
Patients with history of UTI and catheter dependence are more likely to experience a complication while waiting for HoLEP. Having a wait time complication can significantly delay surgery date by up to 30 days, and patients experiencing complication preoperatively are more likely to experience further complications postoperatively. Efforts are needed to expedite and improve access to necessary BPH procedures.
良性前列腺增生(BPH)手术,包括钬激光前列腺剜除术(HoLEP),通常被认为是选择性手术,导致许多患者等待干预。HoLEP的等待时间因多种因素而异,但术前等待期并发症的发生率和影响尚不清楚。我们试图揭示在等待手术期间出现并发症的患者接受HoLEP的结果。
我们对2021年1月至2023年8月期间在一家大型中心接受HoLEP的患者的前瞻性维护数据库进行了回顾性研究。记录手术病例申请日期、并发症发生日期和HoLEP日期。收集并分析术前、术中和术后特征。使用SPSS软件进行统计分析,p < 0.05表示有统计学意义。
在此时间段内,我们在数据库中识别出918例患者,其中74例在等待HoLEP期间出现并发症。术前平均前列腺体积为122.7毫升。并发症包括8例心脏事件和37例泌尿系统事件。并发症使等待时间增加了31.2天。发生心脏并发症的患者等待了113.5天(p = 0.013)。等待期间出现并发症的患者更有可能正在服用良性前列腺增生(BPH)药物、依赖导尿管,并且在手术6个月内发生尿路感染(UTI)。并发症组术后90天并发症发生率为31.5%,非并发症组为20.4%。经历等待时间并发症的患者术后导尿管留置时间也更长,急诊就诊次数增加。
有尿路感染病史和依赖导尿管的患者在等待HoLEP期间更有可能出现并发症。出现等待时间并发症可使手术日期显著延迟多达30天,术前出现并发症的患者术后更有可能出现进一步并发症。需要努力加快并改善获得必要的BPH手术的机会。