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HoLEP:治疗良性前列腺增生的新金标准。

HoLEP: the new gold standard for surgical treatment of benign prostatic hyperplasia.

机构信息

Department of Urology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

出版信息

Can J Urol. 2021 Aug;28(S2):6-10.

Abstract

UNLABELLED

INTRODUCTION Transurethral resection of the prostate (TURP) was considered the "gold standard" surgical treatment for medication-refractory benign prostatic hyperplasia (BPH) for decades. With the desire to reduce hospital stay, complications, and cost, less invasive procedures gained usage in the 1990's. With the advent of a soft tissue morcellator, holmium laser enucleation of the prostate (HoLEP) was introduced as an efficacious alternative to TURP and due to its advantageous side effect profile compared to TURP, has grown in popularity ever since. HoLEP has become a size-independent guideline endorsed procedure of choice for the surgical treatment of BPH.

MATERIALS AND METHODS

We provide a review on the evolution of HoLEP as a gold standard compared to the historical reference procedures for BPH, and provide a review of emerging laser technologies.

RESULTS

A growing body of literature has shown HoLEP to be a safe and efficient procedure for the treatment of BPH for all prostate sizes. Long term studies have proven the durability of HoLEP, as a first line surgical therapy for BPH.

CONCLUSIONS

HoLEP is a proven modality for the surgical treatment of BPH. It can be performed on patients with high risk for postoperative bleeding, or after previous prostate reducing procedures. HoLEP is the only procedure that is AUA guideline-endorsed for all prostate sizes for the surgical treatment of BPH. Given these considerations, HoLEP has become the new gold-standard for the surgical treatment of BPH.

摘要

目的

介绍 经尿道前列腺切除术(TURP)曾被认为是治疗药物难治性良性前列腺增生(BPH)的“金标准”手术治疗方法数十年。为了减少住院时间、并发症和成本,90 年代开始使用更具侵入性的手术。随着软组织捣碎器的出现,钬激光前列腺剜除术(HoLEP)作为 TURP 的有效替代方法被引入,与 TURP 相比,它具有优势的副作用谱,自那时以来,HoLEP 的使用越来越普及。HoLEP 已成为 BPH 手术治疗的一种与前列腺体积无关的指南推荐首选方法。

材料和方法

我们回顾了 HoLEP 的发展历程,将其与 BPH 的历史参考手术进行了比较,并对新兴的激光技术进行了综述。

结果

越来越多的文献表明,HoLEP 是治疗各种前列腺体积 BPH 的安全有效的方法。长期研究证明了 HoLEP 的耐久性,作为 BPH 的一线手术治疗方法。

结论

HoLEP 是治疗 BPH 的一种成熟方法。它可用于术后出血风险高或先前前列腺缩小手术的患者。HoLEP 是唯一一种被 AUA 指南推荐用于治疗所有前列腺体积 BPH 的手术方法。考虑到这些因素,HoLEP 已成为治疗 BPH 的新标准。

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