• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

HoLEP:治疗良性前列腺增生的新金标准。

HoLEP: the new gold standard for surgical treatment of benign prostatic hyperplasia.

机构信息

Department of Urology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

出版信息

Can J Urol. 2021 Aug;28(S2):6-10.

PMID:34453422
Abstract

UNLABELLED

INTRODUCTION Transurethral resection of the prostate (TURP) was considered the "gold standard" surgical treatment for medication-refractory benign prostatic hyperplasia (BPH) for decades. With the desire to reduce hospital stay, complications, and cost, less invasive procedures gained usage in the 1990's. With the advent of a soft tissue morcellator, holmium laser enucleation of the prostate (HoLEP) was introduced as an efficacious alternative to TURP and due to its advantageous side effect profile compared to TURP, has grown in popularity ever since. HoLEP has become a size-independent guideline endorsed procedure of choice for the surgical treatment of BPH.

MATERIALS AND METHODS

We provide a review on the evolution of HoLEP as a gold standard compared to the historical reference procedures for BPH, and provide a review of emerging laser technologies.

RESULTS

A growing body of literature has shown HoLEP to be a safe and efficient procedure for the treatment of BPH for all prostate sizes. Long term studies have proven the durability of HoLEP, as a first line surgical therapy for BPH.

CONCLUSIONS

HoLEP is a proven modality for the surgical treatment of BPH. It can be performed on patients with high risk for postoperative bleeding, or after previous prostate reducing procedures. HoLEP is the only procedure that is AUA guideline-endorsed for all prostate sizes for the surgical treatment of BPH. Given these considerations, HoLEP has become the new gold-standard for the surgical treatment of BPH.

摘要

目的

介绍 经尿道前列腺切除术(TURP)曾被认为是治疗药物难治性良性前列腺增生(BPH)的“金标准”手术治疗方法数十年。为了减少住院时间、并发症和成本,90 年代开始使用更具侵入性的手术。随着软组织捣碎器的出现,钬激光前列腺剜除术(HoLEP)作为 TURP 的有效替代方法被引入,与 TURP 相比,它具有优势的副作用谱,自那时以来,HoLEP 的使用越来越普及。HoLEP 已成为 BPH 手术治疗的一种与前列腺体积无关的指南推荐首选方法。

材料和方法

我们回顾了 HoLEP 的发展历程,将其与 BPH 的历史参考手术进行了比较,并对新兴的激光技术进行了综述。

结果

越来越多的文献表明,HoLEP 是治疗各种前列腺体积 BPH 的安全有效的方法。长期研究证明了 HoLEP 的耐久性,作为 BPH 的一线手术治疗方法。

结论

HoLEP 是治疗 BPH 的一种成熟方法。它可用于术后出血风险高或先前前列腺缩小手术的患者。HoLEP 是唯一一种被 AUA 指南推荐用于治疗所有前列腺体积 BPH 的手术方法。考虑到这些因素,HoLEP 已成为治疗 BPH 的新标准。

相似文献

1
HoLEP: the new gold standard for surgical treatment of benign prostatic hyperplasia.HoLEP:治疗良性前列腺增生的新金标准。
Can J Urol. 2021 Aug;28(S2):6-10.
2
Feasibility of holmium laser enucleation of the prostate (HoLEP) for recurrent/residual benign prostatic hyperplasia (BPH).钬激光前列腺剜除术(HoLEP)治疗复发性/残留良性前列腺增生(BPH)的可行性。
BJU Int. 2012 Dec;110(11 Pt C):E845-50. doi: 10.1111/j.1464-410X.2012.11290.x. Epub 2012 Jun 15.
3
Holmium laser enucleation of the prostate (HoLEP): a review and update.钬激光前列腺剜除术(HoLEP):综述与更新
Can J Urol. 2019 Aug;26(4 Suppl 1):13-19.
4
Holmium laser enucleation of the prostate (HoLEP): size-independent gold standard for surgical management of benign prostatic hyperplasia.钬激光前列腺剜除术(HoLEP):良性前列腺增生症手术治疗的非尺寸依赖性金标准。
Can J Urol. 2020 Aug;27(S3):44-50.
5
In 2013, holmium laser enucleation of the prostate (HoLEP) may be the new 'gold standard'.2013 年,钬激光前列腺剜除术(HoLEP)可能成为新的“金标准”。
Curr Urol Rep. 2012 Dec;13(6):427-32. doi: 10.1007/s11934-012-0279-4.
6
Benign Prostatic Hyperplasia Endoscopic Surgical Procedures in Kidney Transplant Recipients: A Comparison Between Holmium Laser Enucleation of the Prostate, GreenLight Photoselective Vaporization of the Prostate, and Transurethral Resection of the Prostate.肾移植受者良性前列腺增生的内镜手术治疗:钬激光前列腺剜除术、绿激光前列腺汽化术和经尿道前列腺电切术的比较。
J Endourol. 2020 Feb;34(2):184-191. doi: 10.1089/end.2019.0430. Epub 2019 Nov 8.
7
HoLEP techniques - lessons learned.HoLEP 技术——经验教训。
Can J Urol. 2021 Aug;28(S2):11-16.
8
Comparison of holmium laser enucleation and transurethral resection of prostate in benign prostatic hyperplasia: a systematic review and meta-analysis.钬激光前列腺剜除术与经尿道前列腺电切术治疗良性前列腺增生的比较:系统评价和荟萃分析。
J Int Med Res. 2023 Aug;51(8):3000605231190763. doi: 10.1177/03000605231190763.
9
The diagnostic value of prostate cancer between holmium laser enucleation of the prostate and transurethral resection of the prostate for benign prostatic hyperplasia: A retrospective comparative study.钬激光前列腺剜除术与经尿道前列腺电切术治疗良性前列腺增生的前列腺癌诊断价值:一项回顾性对比研究。
Int J Surg. 2020 Jul;79:217-221. doi: 10.1016/j.ijsu.2020.05.025. Epub 2020 May 21.
10
[Transurethral resection of the prostate versus transurethral holmium laser enucleation of the prostate for benign prostatic hyperplasia with bladder detrusor overactivity].经尿道前列腺切除术与经尿道钬激光剜除术治疗合并膀胱逼尿肌过度活动症的良性前列腺增生症的对比研究
Zhonghua Nan Ke Xue. 2016 Aug;22(8):720-724.

引用本文的文献

1
The regular use of finasteride before transurethral laser resection of the prostate helps reduce bleeding.在经尿道前列腺激光切除术之前定期使用非那雄胺有助于减少出血。
Lasers Med Sci. 2025 Sep 15;40(1):357. doi: 10.1007/s10103-025-04618-1.
2
Aquablation versus HoLEP: Propensity score matching analysis of functional outcomes and ejaculation preservation.水刀消融术与holmium激光前列腺剜除术:功能结局及射精功能保留的倾向评分匹配分析
Investig Clin Urol. 2025 Sep;66(5):431-438. doi: 10.4111/icu.20250055.
3
Impact of preoperative fasting duration and prostate mass on postoperative bleeding after transurethral enucleation of the prostate: A risk factor analysis.
术前禁食时间和前列腺质量对经尿道前列腺剜除术后出血的影响:一项危险因素分析。
J Int Med Res. 2025 Aug;53(8):3000605251369111. doi: 10.1177/03000605251369111. Epub 2025 Aug 25.
4
Waiting for HoLEP-outcomes when complications arise in the preoperative period.术前出现并发症时等待经尿道前列腺剜除术(HoLEP)的结果。
World J Urol. 2025 Aug 18;43(1):499. doi: 10.1007/s00345-025-05871-3.
5
MoLEP vs. HoLEP for BPH: A 3-Year Greek Single-Center Retrospective Comparative Cohort Study on 1368 Cases.经尿道前列腺剜除术与经尿道前列腺激光剜除术治疗良性前列腺增生症:一项针对1368例病例的为期3年的希腊单中心回顾性比较队列研究。
Cancers (Basel). 2025 May 10;17(10):1608. doi: 10.3390/cancers17101608.
6
Outcomes of holmium laser enucleation of the prostate in men with a history of prostatitis: a retrospective study.有前列腺炎病史男性患者行钬激光前列腺剜除术的疗效:一项回顾性研究。
Ther Adv Urol. 2025 May 17;17:17562872251338430. doi: 10.1177/17562872251338430. eCollection 2025 Jan-Dec.
7
Holmium laser enucleation of the prostate versus transurethral resection of the prostate in treatment of benign prostatic hyperplasia: A meta-analysis of 13 randomized control trials.钬激光剜除术与经尿道前列腺切除术治疗良性前列腺增生症的比较:13项随机对照试验的荟萃分析
Curr Urol. 2025 Jan;19(1):6-16. doi: 10.1097/CU9.0000000000000257. Epub 2024 Sep 27.
8
Low-power versus high-power laser for holmium laser enucleation of prostate: systematic review and meta-analysis.低功率与高功率激光用于钬激光前列腺剜除术:系统评价与Meta分析
World J Urol. 2025 Apr 17;43(1):228. doi: 10.1007/s00345-025-05621-5.
9
Querying the capability of the post-HoLEP endoscopic aspect of the membranous urethral mucosa in predicting urinary incontinence: a prospective AI-based analysis.探讨经尿道前列腺剜除术后膜性尿道黏膜内镜表现预测尿失禁的能力:一项基于人工智能的前瞻性分析。
World J Urol. 2025 Mar 12;43(1):165. doi: 10.1007/s00345-025-05555-y.
10
Comparison of Perioperative Outcomes of Holmium Laser Enucleation of the Prostate for Standard (≤149 ml) Versus Very Large (≥150 ml) Prostate Glands: Retrospective Analysis of a Propensity Score Matched Cohort of 326 Patients.标准体积(≤149毫升)与超大体积(≥150毫升)前列腺的钬激光剜除术围手术期结果比较:对326例患者的倾向评分匹配队列的回顾性分析
Eur Urol Open Sci. 2024 Nov 18;71:15-21. doi: 10.1016/j.euros.2024.10.019. eCollection 2025 Jan.