Sinkler Margaret A, Kuo Andy, Wang Margaret, Strony John T, Fortier Luc M, Boes Kirsten, Ochenjele George
From the Department of Orthopaedics (Dr. Sinkler, Dr. Strony, Dr. Fortier, Ms. Boes, and Dr. Ochenjele), University Hospitals Cleveland Medical Center, Cleveland, OH, and the Case Western Reserve University School of Medicine (Dr. Kuo and Dr. Wang), Cleveland, OH.
J Am Acad Orthop Surg Glob Res Rev. 2025 Aug 18;9(8). doi: 10.5435/JAAOSGlobal-D-24-00329. eCollection 2025 Aug 1.
This study aims to determine the incidence of pre- and postoperative nerve injuries associated with humeral shaft fractures.
Three hundred eight humeral shaft fractures (Orthopaedic Trauma Association/Arbeitsgemeinschaft fur Osteosynthesefragen 12) underwent surgical treatment from 2009 to 2020 were reviewed. Nerve injury was identified by motor or sensory deficit. Patients were grouped by mechanism. Each cohort was evaluated for rate of nerve injury and exploration, onset of nerve recovery, and predictors of nerve injury.
Twenty-four sustained gunshot wounds (GSWs), 73 high-energy injury mechanisms, and 211 low-energy injury mechanisms. Fifty-six preoperative and 14 postoperative nerve injuries were identified. Eight patients (33%) in the GSW cohort, 22(31%) with high-energy mechanisms, and 26 (13%) with low-energy mechanisms had a preoperative nerve injury (P < 0.001). One patient (4%) in the GSW cohort, 0 with high-energy mechanisms, and 13 (7%) with low-energy mechanisms had a postoperative nerve injury (P = 0.24). Preoperative nerve injuries from GSWs and high-energy mechanisms required more time for nerve recovery (6.8 vs. 5.2 vs. 4.0 months). Regression analysis showed that GSW (odds ratio = 4.79, P = 0.038, confidence interval = 1.79 to 15.87) and high-energy mechanisms (odds ratio = 2.34, P = 0.049, confidence interval = 1.004 to 5.784) were associated with preoperative nerve injury.
GSWs and high-energy mechanisms have higher incidence of nerve injury associated with humeral shaft fractures and may require more time to recover.
本研究旨在确定肱骨干骨折术前和术后神经损伤的发生率。
回顾了2009年至2020年接受手术治疗的308例肱骨干骨折(骨科创伤协会/骨科学术研究联合会12型)。通过运动或感觉功能障碍确定神经损伤。患者按损伤机制分组。评估每个队列的神经损伤和探查率、神经恢复开始时间以及神经损伤的预测因素。
24例为枪伤,73例为高能量损伤机制,211例为低能量损伤机制。共识别出56例术前神经损伤和14例术后神经损伤。枪伤队列中有8例患者(33%)、高能量损伤机制组中有22例(31%)、低能量损伤机制组中有26例(13%)存在术前神经损伤(P<0.001)。枪伤队列中有1例患者(4%)、高能量损伤机制组中无、低能量损伤机制组中有13例(7%)存在术后神经损伤(P=0.24)。枪伤和高能量损伤机制导致的术前神经损伤恢复所需时间更长(分别为6.8个月、5.2个月和4.0个月)。回归分析显示,枪伤(比值比=4.79,P=0.038,置信区间=1.79至15.87)和高能量损伤机制(比值比=2.34,P=0.049,置信区间=1.004至5.784)与术前神经损伤相关。
枪伤和高能量损伤机制与肱骨干骨折相关的神经损伤发生率较高,且恢复时间可能更长。